B5-Communicable diseases Flashcards
(72 cards)
What is the definition of a pathogen?
A disease causing micro-organism
What are the types of pathogen?
Protist
Fungi
Virus
Bacterium
Compare the features of bacterium and viruses in terms of size, treatment, reproduction, survival, living and pathogenicity.
Bacteria are bigger/viruses are smaller
Bacteria are treated with antibiotics/Viruses have no treatment
Bacteria divide via binary fission/viruses divide inside host cells
Bacteria can survive without a host/viruses cannot
Bacterium are alive/viruses are not
Only a few bacterium a pathogenic/all viruses are pathogenic
How do bacteria cause disease?
May release toxins that damage cells
May damage host cells directly
How do viruses cause disease?
They inject genetic information (RNA) into the nucleus of host cells, and the host cell will use this to divide and make more virus particles.
The virus particles will leave the host cell to infect neighbouring particles, and sometimes the host cell dies when the virus particles leave it
What are the methods of spreading pathogens?
Aerosol
Direct contact
Water
What does bacteria culture mean?
To grow bacteria
What is a bacterial colony?
A large number of bacterial cells growing together in a lump
What is a culture medium?
Material that is used to grow the test subject (agar)
What does inoculate mean?
To place the bacteria cells onto the culture medium
How is equipment sterilised?
In an autoclave which uses steam and high pressure to sterilise equipment used in growing bacteria
How do prokaryotic cells divide?
Binary fission
How is bacteria cultured?
Sterilise the inoculating loop by placing over a Bunsen burner until it turns red
Open agar plate slightly at an angle to minimise exposure
Use inoculating loop to collect bacteria
Streak the bacteria gently across the agar surface
Clos petri dish immediately
secure petri dish with tape-leave gap for oxygen
Label with date and type of bacteria
Turn petri dish upside down
Incubate at 25 degrees for 24-48 hrs
Examine bacterial colony
During bacteria culture, why is the petri dish turned upside down?
To prevent condensation droplets from falling onto the bacteria and drowning them and also contaminating them
Why should schools incubate at a maximum of 25 degrees?
To avoid human pathogens which grow at 37 degrees
Why might industry and hospitals incubate bacteria at 37 degrees?
To get faster growth
What does mean division time for bacteria mean?
The average time needed by a species of bacteria to divide once by binary fission
What is the equation for the number of bacteria at the end of a growth period?
Number of bacteria at start X 2^number of divisions
What did Ignaz Semmelweis do?
Discovered that pathogens were carried by doctors who did not wash their hands
What did Louis Pasteur do?
Showed that microbes caused disease
Developed the first vaccines against smallpox, anthrax and rabies
What are vectors?
Organisms that pass on a pathogen without being infected themselves like mosquitos
How do vaccines work?
An antigen is introduced into the body
Immune system/lymphocytes develop antibodies against the antigen and memory cells
If the patient is in contact with the real pathogen, the lymphocytes will produce antibodies and destroy it before symptoms develop
What are the features of measles?
It is a virus
Symptoms include fever, red skin and rash
It is spread by aerosol
Can cause blindness, brain damage or death
It has no treatments
If infected, you must be isolated
Can be prevented with vaccination
What are the features of HIV/AIDS?
It is a virus
Symptoms include flu and other symptoms of other diseases
It is spread by sexual contact and exchange of bodily fluids
Causes a non functioning immune system, and death due to other diseases
If infected, you must not donate blood, use contraception and not share needles
It can be treated with anti-retroviral drugs
It can be prevented by blood screening and contraception