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MM3 Leesy > B6.024 - Dermatopathology FLIP Prework > Flashcards

B6.024 - Dermatopathology FLIP Prework Flashcards

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1
Q

epidermal inflammatory diseases

A
  1. psoriasis
  2. eczema
  3. lupus erythematosus
  4. lichen planus
  5. erythema multiforme
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2
Q
A

psoriasis

Genetic/environmental etiology

4% pop

beefy red plaques with silver scale

scalp, elbowsm knees, sacrum

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3
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4
Q

allergic skin diseases: eczemas

A

allergic contact eczema - potent exogenous allergen

atopic eczema - endogenous predisposition

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5
Q
A

allergic contact dermatitis

caused by contact with external allergen

poison ivy

nickel

balsam of peru

neomycin

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6
Q
A

atopic eczema

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9
Q
A

lupus erythematosus

Anti DNA Antibodies (ANA)

may affect any organ, butterfly malar rash, female>male, african american >

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10
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11
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12
Q
A

lichen planus

pruritic

purple

polygonal

papules

Wickam striae

symmetric distrubution

30-60 yo

hepatitis C, medication, contact allergen

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13
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14
Q
A

erythema multiforme

acute eruption

HSV, mycoplasma

young adults

target lesions

self limited

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15
Q
A

acute eruption

HSV, mycoplasma

young adults

target lesions

self limited

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16
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A
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17
Q

blistering skin diseases

A
  1. pemphigus
  2. pemphigoid
  3. dermatitis herpetiformis
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18
Q
A

pemphigus vulgaris

40-60 yo

cutaneous erosions/oral ulcers

intact blisters are rare

Painful! Not itchy

Upper trunk and head

+nikolsky

Rx CTSD, immunosuppression

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19
Q
A

pemphigus vulgaris

40-60 yo

cutaneous erosions/oral ulcers

intact blisters are rare

Painful! Not itchy

Upper trunk and head

+nikolsky

Rx CTSD, immunosuppression

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20
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21
Q
A

bullous pemphigoid

elderly pts

tense blisters and vesicles

lower abd, thighs, FAs

10-30% involve mucosa

severe pruritis

negativec nikolky sign

rx. topical / systemic CTSDs

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22
Q
A

Elderly, tense blisters and vesicles

lower abd, thighs, FAs

severe pruritis

negative nikolsky sign

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23
Q
A

elderly, tense blisters, vesicles

severe pruritis

negative niklosky sign

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24
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dermatitis herpetiformis broad age range grouped pruritic papules knees, elbows, sacrum, nape of neck, scalp associated with HLD DQ2, DQ8 CELIACS dapsone, gluten free diet tx
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dermatitis herpetiformis broad age range grouped pruritic papules knees, elbows, sacrum, nape of neck, scalp associated with HLD DQ2, DQ8 CELIACS dapsone, gluten free diet tx
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dermatitis herpetiformis broad age range grouped pruritic papules knees, elbows, sacrum, nape of neck, scalp associated with HLD DQ2, DQ8 CELIACS dapsone, gluten free diet tx
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dermal/SQ inflammatory diseases
1. acne 12. rosacea 3. urticaria 4. leukocytoclastic vasculitis 5. erythema nodosum
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acne vulgaris 85% of young adults onset 9-11 papules, pustules, nodules, comedones face/back/chest increased sebum production p. acnes lipase \>\> irritating fatty acids follicular occlusion Rx benzoyl peroxide, retinoid, ABX, OCP
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acne vulgaris 85% of young adults 9-11 papules, pustules, nodules, comedones face/back/chest increased sebum production p acnes lipase \>\>\> irritating fatty acids follicular occlusion rx. benzoyl peroxide, retinoid, ABX, OCP
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rosacea 1-10% prevalence fair skinned adults 30-50 redness and dilated blood vessels: nose, cheeks, forehead, chin ocular: gritty sensation phymatous: nodular thickening papulopustular: like acne rx avoid triggers, topical oral ABX
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rosacea 1-10% prevalence fair skinned adults 30-50 redness and dilated blood vessels: nose, cheeks, forehead, chin ocular: gritty sensation phymatous: nodular thickening papulopustular: like acne rx avoid triggers, topical oral ABX
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urticaria AKA wheals, hives 1-5% prevalence transiet plaques, often annular pruritic and edematous angioedema, mast cell degranulation T1 HS dermatographism rx. antihistamines
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urticaria AKA wheals, hives 1-5% prevalence transiet plaques, often annular pruritic and edematous angioedema, mast cell degranulation T1 HS dermatographism rx. antihistamines
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urticaria AKA wheals, hives 1-5% prevalence transiet plaques, often annular pruritic and edematous angioedema, mast cell degranulation T1 HS dermatographism rx. antihistamines
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leukocytoclastic vasculitis all ages, mainly adults palpable purpura lower extermities, pressure points, dependent areas 50% idiopathic remainder associated with infections, drug reactions, autoimmune illnesses T3HS immune complex deposits rare systemic involvement ALWAYS GET A UA rx. supportive, colchicine
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erythema nodosum tender nodules, shins young women T4 HS delayed type 50% idiopathic sarcoid, drugs, IBD, URI rx. bed rest, NSAIDs
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skin infections/infestations
1. viral wart 2. molluscum contagiosum 3. impetigo 4. tinea 5. deep fungal 6. insect bites 7. scabies
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viral wart aka verruca vulgaris very common, children/YA keratotic papules hands, feet, face HPV rx. cryo/surgery, topicals
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koilocyte is a halo around the cell indicating HPV
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molluscum contagiosum children, YA, HIV+ umbillicated papules face, neck, axillae, trunk, thighs buttocks, genitals MC virus (a pox virus) direct transmission Rx: cryo, curettage, topical imiquimod and others
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Molluscum contagiosum MC virus
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Impetigo common in kids face/extremities erosions and vesicles honey colored crusts blitsters s. aureus (95%0 s. pyogenes --\> glomerulonephritis topical ABX
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Impetigo common in kids face/extremities erosions and vesicles honey colored crusts blitsters s. aureus (95%0 s. pyogenes --\> glomerulonephritis topical ABX
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tinea mainly post pubertal dermatophtes esp trichophytum rubrum transmission by direct contact annular plaques with pusutles, active border scalp, foot, body, toenal rx topical or systemic antifungals
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tinea mainly post pubertal dermatophtes esp trichophytum rubrum transmission by direct contact annular plaques with pusutles, active border scalp, foot, body, toenal rx topical or systemic antifungals
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tinea mainly post pubertal dermatophtes esp trichophytum rubrum transmission by direct contact annular plaques with pusutles, active border scalp, foot, body, toenal rx topical or systemic antifungals
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deep fungal infection - aspergillosis immunocompromised papules, nodules, necrosis occur at sites of trauma may also disseminate from lung infection aspergillus fumigatus 75-90% mortality in disseminated disease Rx STAT systemic antifungals, surgical debridement if localized
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insect bite reaction excoriated papules mosquitoes, fleas, ticks, chiggers, bedbugs, spiders young, immunodeficient rx remove ticks, topical antipruritics
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scabies children, ya finger webs, axillae, umbilicaus, areaolas pruritic papules itching worse at night direct transmission rx ivermectin pill or pemethrin cream
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KOH preparation nastiest shit ive seen in my life

MM3 Leesy (12 decks)

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