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Immunology and Microbiology > Bacteria > Flashcards

Flashcards in Bacteria Deck (19):
1

Vibrio Cholerae Properties (3)

Gram negative, Extracellular, Comma shaped

2

Staph Aureus Properties (3)

Gram positive, Extracellular, Round shaped

3

Neisseria Meningitidis Properties (3)

Gram negative, Extracellular, dipplococcus

4

Strep Pyogenes Properties (3)

Gram positive, Extracellular, round shaped

5

Shigella Properties (3)

Gram negative, intracellular rod shaped

6

Salmonella Properties (3)

Gram negative, intracellular, rod shaped

7

Vibrio Cholera Toxins + mechanism

Cholera toxin - binds to GM1 ganglioside, decreases GTPase, increases adenylate cyclase, electrolyte and water loss

8

Staph Aureus toxins (5)

coagulase, spreading factor, deoxyribonuclease, superantigens, exfoliatives

9

Neisseria Meningitidis toxins (1)

LPS (septic shock)

10

Strep toxins (3)

SpeA +C (superantigens), SpeB (cysteine protease)

11

Shigella toxins (2)

Shiga toxin (enterotoxin) (Stx1 and 2- inhibit protein synthesis in infected cells)

12

Action of Beta-lactams + example

Penicillin, inhibits cross-linking in peptidoglycan synthesis

13

Action of Macrolides + example

Tetracycline, inhibits protein synthesis by binding to 30s subunit of ribosome

14

Action of aminoglycosides

inhibition of membrane function

15

Action of sulphonamides

antimetabolites

16

Action of Quinolones

inhibition of nucleic acid synthesis

17

Method of penicillin resistance (2)

beta-lactamase - breaks the antibiotic structure, and target site modification

18

method of tetracycline resistance (1)

efflux pump

19

transfer of resistance mechanisms to antibiotics (4)

plasmid-transformation, point mutation, plasmid-conjugation, transduction