Bacteria and archaea cell membrane structure Flashcards

1
Q

What 2 structures make up the cell envelope?

A

The cell membrane and cell wall

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2
Q

What does the cell membrane do in bacteria?

A

Selective barrier that keeps the outside out and the inside in

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3
Q

What are bacterial cell membranes made out of?

A

Phospholipids, proteins, carbs

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4
Q

What is the structure of a phospholipid?

A

A glycerol with a phosphate attached to one carbon, and fatty acids attached to the other two. Small polar head group attached to the phosphate

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5
Q

What are hopanoids?

A

Rigid, planar molecules analogous to sterols in eukaryotic membranes, but aren’t sterols even though they look like one

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6
Q

What do hopanoids do?

A

Stabilize bacterial membranes and regulate fluidity. Prevents phospholipids from packing too tightly in low temps and stops them becoming too loose in high temps

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7
Q

What type of bacteria tend to have hopanoids in their membranes? Why?

A

Soil bacteria. They’re exposed to a wide range of temperatures

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8
Q

What is the only bacteria that has cholesterol in its membrane? Why?

A

Mycoplasma. They’re intracellular pathogens with no cell walls, so they use cholesterol to strengthen their membranes

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9
Q

Where does Mycoplasma get its cholesterol?

A

Steals it from the host. No bacteria has been found to make cholesterol

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10
Q

What are the 2 types of membrane proteins?

A

Integral and peripheral

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11
Q

What are two ways archaeal membrane lipids are different than bacterial lipids?

A

Ether linkages instead of ester linkages and phytanyls instead of fatty acids

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12
Q

How do archaea attach the hydrophobic tails of their phophoslipids to the glycerol?

A

Ether linkages

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13
Q

Why do archaeal membrane lipids have ether linkages instead of ester linkages like bacteria?

A

Ether linkages are more stable in extreme conditions. Keeps the archaeal membranes stable at high temps

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14
Q

What do archaeal membrane lipids use instead of fatty acids?

A

Phytanyl groups

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15
Q

What are phytanyl groups made of?

A

4 isoprene units stuck together

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16
Q

What are biphytanyl lipids?

A

2 phytanyl lipids covalently attached in the middle to form one long phytanyl chain that is attached to a glycerol with ether linkages on either end

17
Q

How do phytanyl lipids assemble into the membrane?

A

As a bilayer

18
Q

How do biphytanyl lipids assemble into the membrane?

A

As a monolayer

19
Q

What type of archaea have biphytanyl membrane lipids?

A

Hyperthermophiles. The lipids are very resistant to heat disruption

20
Q

How can biphytanyl chains be modified to allow even tighter packing?

A

Can have 5-membered rings at various positions within the chain

21
Q

What is the advantage of having rings in a phytanyl lipid?

A

The rings can stack together and allow even tighter packing for decreased membrane fluidity. Also helps with living at extremely high temps