Bacterial vaginosis Flashcards

1
Q

What is bacterial vaginosis?

A

Overgrowth of anaerobic bacteria in vagina

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2
Q

What causes bacterial vaginosis?

A

Loss of lactobilli - friendly bacteria
Increases risk of developing STIs

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2
Q

What causes bacterial vaginosis?

A

Loss of lactobilli - friendly bacteria
Increases risk of developing STIs

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3
Q

What is the role of lactobacilli

A

Produce lactic acid keeps vaginal pH low - under 4.5 - prevents other bacteria from overgrowing

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4
Q

What allows bacteria to multiply in BV

A

Reduced lactobilli allows pH to rise -> alkaline environment enables anaerobic bacteria to multiply

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5
Q

Anaerobic bacteria ass with BV

A

Gardnerella vaginalis (most common)
Mycoplasma hominis
Prevotella species

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6
Q

What other infections does BV often co-occur with

A

Candidiasis
Chlamydia
Gonorrhea

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7
Q

Risk factors for bacterial vaginosis

A

Multiple sexual partners
Excessive vaginal cleaning - douching, cleaning products, washes etc
Recent antibiotics
Smoking
Copper coil

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8
Q

What women are less at risk of BV

A

Combined pill
Using condoms effectively

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9
Q

Presentation of BV

A

Fishy smelling wateru grey or white vaginal discharge
50% asymtpomatic

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10
Q

What symptoms are not typically ass with BV and suggest alternative cause or co-occuring infection

A

Itching
Irritation
Pain

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11
Q

How confirm typical discharge

A

Complete high vaginal swab and exclude other causes of symptoms
Not required if typucal symptosm and low risk of UTI

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12
Q

What is normal vaginal pH

A

3.5-4.5

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13
Q

Investigations for BV

A

Standard charcoal vaginal swab - for microscopy
High vaginal swab - during speculum - test for chlamydia and gonorrhea
Self taken low vaginal swab

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14
Q

Findings on microscopy of BV

A

Clue cells - epithelial cells from cervix that have bacteria stuck inside them - gardnerella vaginalis

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15
Q

What bacteria is normally found inside clue cells

A

Gardnerella vaginalis

16
Q

What do clue cells signal on microscopy

A

BV

16
Q

What do clue cells signal on microscopy

A

BV

17
Q

What is the antibiotic of choice fr BV

A

Metronidazole (for anaerobic bacteria)
Orally or vaginal gel

18
Q

What is the alternative choice to metronidazole

A

Clindamycin
Less optimal

19
Q

What should avoid on metronidazole

A

Avoid alcohol

20
Q

What does alcohol and metronidazole cause

A

Disulfiram-like reaction - nausea and vomitting, flushing and sometimes severe symptoms of shock and angioedmea

21
Q

Complications ass with BV in pregnant women

A

Miscarriage
Preterm delivery
PROM
Chorioamnionitis
Low birth weight
Postpartum endometritis