Bartonella Flashcards

1
Q

respiration
fastidious?
gram
shape
motility
facultative? intracellular?
opportunistic?

A

aerobic
fastidious
gram negative
coccobacilli
motile – lophotrichous flagella
facultative intracellular bacteria – hide in erythrocytes
opportunistic – bartonellosis

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2
Q

what cells do they hide in

A

erythrocytes

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3
Q

hosts
vectors

A

hosts – wild and domestic animals, particularly cats
vectors – arthropods, cat fleas

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4
Q

b henselae
vectors
reservoir
diseases

A

cat fleas vectors
cat reservoirs
cat scratch disease, endocarditis, bacteremia

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5
Q

b bacilliformis
vectors
reservoir
diseases

A

sand flies vectors
human reservoirs
carrion’s disease

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6
Q

b quintana
vectors
reservoir
diseases

A

body lice vectors
humans reservoir
trench fever

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7
Q

b koehlerae
vectors
reservoir
diseases

A

cat fleas vectors
cat reservoirs
endocarditis, bacteremia, tissue infections

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8
Q

b clarridgeiae
vectors
reservoir
diseases

A

cat fleas vectors
cats reservoirs
endocarditis, bacteremia, tissue infections

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9
Q

b vinsonii subspecies berkhoffii
vectors
reservoir
diseases

A

brown dog tick vectors
cats, foxes, coyotes, dogs reservoirs
endocarditis, bacteremia, tissue infections

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10
Q

b bovie
vectors
reservoir
diseases

A

biting flies vectors
ruminant reservoirs
endocarditis

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11
Q

do most cats get disease

A

most cats asymptomatic, subclinical bacteremia

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12
Q

what disease can cats get, who susceptible

A

feline bartonellosis
kittens, stress, concurrent disease

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13
Q

is it zoonotic

A

yes – cat scratch fever

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14
Q

how is cat scratch fever transmitted

A

infected flea poop gets under cat claws from grooming
cat scratches someone
bacteria gets in scratch wound

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15
Q

disease in immunocompetent people

A

local lymphadenopathy
endocarditis

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16
Q

disease in immunocompromised people

A

bacillary angiomatosis
cutaneous lesions (IL-8)
every organ system affected

17
Q

general symptoms

A

fever
fatigue
loss of appetite
weight lodd

18
Q

virulence

A

multiple flagella
bartonella adhesion A (BadA)
filamentous hemagglutination
twr system – adhesion to erythrocyte
VirB/VirD4-T4SS
iaIAB proteins
hemolysin
intracellular pathogen of erythrocytes

19
Q

what is required for diagnostics

A

repeated testing or combination of tests

20
Q

what kind of media

A

blood enriched media

21
Q

diagnosis

A

warthin starry stain
PCR
ELISA
IFA
histology
radiographs

22
Q

why is serology (ELISA, IFA) not recommended in cats

A

false positive results

23
Q

treatment

A

usually not necessary
antibiotics take 4-6 weeks

24
Q

control

A

no vaccines
prevent cat scratches and bites
flea control