Basic Pharma Flashcards
1
Q
Drug with biggest molecular weight.
A
Alteplase (50,000)
2
Q
Actions of the drug to the body.
A
Pharmacodynamics
3
Q
Actions of the body to the drug.
A
Pharmacokinetics
4
Q
Amount of drug needed to produce an effect
A
Potency
5
Q
What is the first-pass effect?
A
A significant amount of drug is metabolized in the gut wall, portal circulation and liver before it reaches the systemic circulation.
Buccal, sublingual, IM, IV, Inhalational. Topical, Transdermal route -> bypasses the first-pass effect.
Rectal -> partial bypass
6
Q
Slowest route of drug administration.
A
Topical
7
Q
Fraction of the drug that reaches the systemic circulation.
A
Bioavailability
