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psy 311 > behaviour disorders > Flashcards

behaviour disorders Flashcards

1
Q

Psychosis :

A

loss of reality

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2
Q

Schizo-phrenia

Split-brain

A

associations, affect, ambivalence, autism

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3
Q

concordance rate

A

the likely hood that twins will have a certain disease

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4
Q

3 types of Schizo-phrenia

A

• Simple
• Catatonic (waxy flexibility)
Paranoid

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5
Q

Positive symptoms Schizo-phrenia (3)

A

Hallucinations
• Delusions
• Disorganized, agitated speech

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6
Q

The Dopamine Hypothesis Schizo-phrenia

A

excess DA in forebrain
• Support: DA antagonists e.g. (chlorpromazine) reduce symptoms
• Agonists like l-DOPA bring out symptoms

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7
Q

Schizo-phrenia Negative symptoms

A
  • Reduced affect
  • Autism
  • Waxy flexibility
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8
Q

• Disregulation Hypothesis Schizo-phrenia

A

The involvement of SE

– Clozapine ( Clozaril ) D2 and 5HT2 block

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9
Q

Schizo-phrenia 3 methods of treatment

A

Psychosurgery
• Psychotherapy
• Pharmacotherapy

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10
Q

The PCP model

A

– PCP blocks glutamate (NMDA) receptor
– Glutamate excites GABA
– If no GABA inhibition excess dopamine
– Glutamate’s role in cognition (

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11
Q

what can cause negative symptoms

A

brain damage

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12
Q

• Laborit , Charpentier , Delay found that _____ and side effects

A

Chlorpromazine ( Thorazine ) DA Blocker

extra pyramidal effects, tardive dyskenesia

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13
Q

extra pyramidal effects

A

emors, chorea, dystonia, akinesia, akathisia,

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14
Q

tardive dyskenesia

A

bizzarre facial and tongue movements and a stiff neck, and difficulty swallowing.

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15
Q

what are the newer antopsychltics (2)

A

benzodiazepine, Risperidone (Risperdal)

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16
Q

benzodiazepine, Risperidone (Risperdal) blocks_____ and side effects

A

5HT2  and DA2 blocker

agranulocytosis,anxiety,Gestational disorder

17
Q

learned helplessness

A

person suffers from a sense of powerlessness, arising from a traumatic event or persistent failure to succeed. It is thought to be one of the underlying causes of depression.

18
Q

bio behavioral effects depression

A

learned helplessness, nterpersonal stress, frustration punishment,

19
Q

what are the treatment options for depression

A

ECT most effective electric shock, Antidepressents, trans cranial stimulation

20
Q

tranclpromine (parnate is )

A

antidpressent MAO Inhibitor

21
Q

eutonil (pagyline)

A

antidepressent MAO inhibitor

22
Q

phenelezine (Nardil)

A

antidepressent MAO Inhibitor

23
Q

imipiramine (tofranil)

A

tricylic antidepressant

24
Q

amitripyline (elavil)

A

tricylic antidepressant

25
Q

MAO Inhibitor mech. of action, side effects

A

increases biogernic amnes (DA ,5-HT0, hypertension,fatiuge, agitation

26
Q

tricylic mech. of action, side effects

A

blocks reuptake of NE,5-HT, Da, apropine side effects ex dry mouth

27
Q

3 main SSRI’s

A

Prozac, (fluoxetine), zoloft (Sertalin), paxil (paroxetine)

28
Q

Prozac, (fluoxetine) can be used for

A

depression, OCD, anxiety, eating disorders

29
Q

zoloft (Sertalin), is different from prozac

A

shoter half life

30
Q

paxil (paroxetine)…

A

most potent and safest SSRi, least side effects (dry mouth, loss of sex drive),

31
Q

what is the difference between mania and hypomania

A

hyopmania consists of high, optimism ,racing thoughts unrealistic expectations, and the surge of energy
Marina is the same as above + irritability and aggression

32
Q

Theory of mania organic brain disorder

A

Epileptiform activity

Tumors virus and drug, proins

33
Q

Theory of mania biogenic amine hypotheses

A

Excess of noradrenaline

34
Q

Cade— invented Litium salts to __________ and what are the behavioral effects of it

A

Treat mania, effects: sedation ataxia fatigue nausea and slurred speech

35
Q

What is the mechanism of action for lithium salts

A

Increases every uptake of norepinephrine by 30%
inhibits sodium dependent processes and
inhibits the enzyme GSK-3

36
Q

How does treat Tegretol mania

A

Blocks sodium channels ,inhibits enzyme activity

37
Q

How does valproic acid treat mania

A

Inhibits GABT-T make you behave like a monster (teratological effects)

psy 311 (4 decks)

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