Benign Soft Tissue Flashcards

(64 cards)

1
Q

Fibroma is reactive or neoplastic?

A

Reactive to local trauma/irritation

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2
Q

Most common tumor of oral cavity?

A

Fibroma

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3
Q

Fibroma is true neoplasm?

A

no

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4
Q

Histology of fibroma?

A

unencapsulated, collagenized CT covered by SSE

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5
Q

Treatment of fibroma?

A

excision to r/o neoplasm

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6
Q

Recurrence common or rare in fibroma?

A

rare

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7
Q

Fibroma clinical features:
Pigment:
Surface texture:
Sessile/pedunculated?

A

Normal color (can be white from hyperkeratosis)
Smooth
Sessile

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8
Q

Fibromas can be found where in oral cavity?

A

anywhere

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9
Q

Giant cell fibroma important histo feature?

A

Stellate fibroblasts with several nuclei

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10
Q

Variant of giant cell fibroma?

A

Retrocuspid papilla

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11
Q

Retrocuspid papilla location?

A

bilateral, lingual to mand. canines

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12
Q

Pyogenic granuloma aka?

A

Lobular capillary hemangioma, pregnancy tumor

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13
Q

Pyogenic granuloma bad name bc?

A

neither pyogenic or granuloma

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14
Q
Pyogenic granuloma clinical features?
Surface texture
color
Pedunc or sessile
Pain
Blood
A

Smooth/lobulated
Pedunculated/sessile
Pink/red/purple, ulcerated
Bleeds easily

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15
Q

Pyogenic granuloma new vs old difference

A

Vascular when new, collagenized when old

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16
Q

Pyogenic granuloma location?

A

80% gingiva

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17
Q

Variant of pyogenic granuloma arising in healing extraction socket?
Due to what?

A

epulis granulomatosa due to bony sequestra in socket

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18
Q

Pyogenic granuloma histopath features

A

vascular granulation tissue

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19
Q

Pyogenic granuloma treatment

A

excise and remove irritants

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20
Q

Pyogenic granuloma distinguished how from retrocuspid papilla?

A

Pyogenic granuloma is erythematous or hemorrhagic while retrocuspid papilla is pink, small, and bilateral.

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21
Q

Peripheral giant cell granuloma soft tissue counterpart to what?

A

Central giant cell granuloma

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22
Q

Peripheral giant cell granuloma occurs where

A

Gingiva ONLY

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23
Q

Peripheral giant cell granuloma differs from pyogenic granuloma how?

A

more blue-purple, otherwise similar

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24
Q

Radio features of Peripheral giant cell granuloma?

A

cupping resorption of bone

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25
Peripheral giant cell granuloma origin might be soft or hard tissue, need to workup patient for what?
Hyperparathydoidism
26
Peripheral giant cell granuloma histopath features (cells, deposits, and surface)
multinucleated giant cells with background of mesenchymal cells with mitoses, hemorrhage and hemosiderin, ulcerated mucosa overlying
27
Peripheral Ossifying Fibroma occurs where
Gingiva ONLY
28
``` Peripheral Ossifying Fibroma clinical features Surface Color Type What can happen to teeth ```
ulcerated, red-pink, Ped/Sess nodule, rare migration and loosening of teeth
29
Peripheral Ossifying Fibroma histopath features
fibrous, mineralized product
30
Peripheral Ossifying Fibroma can be easily mistaken for?
Pyogenic granuloma
31
Lipoma usually occurs where
trunk or extremities, rarely in oral cavity
32
What is #1 most common mesenchymal neoplasm?
Lipoma
33
Lipoma clinical features?
soft, smooth, pink/yellow
34
Granular cell tumor found where
Oral cavity, usually tongue
35
Granular cell tumor color
pink or yellow
36
Granular cell tumor cell differentiation
neural
37
Granular cell tumor histopath features
pale, eosinophilic granular cytoplasm | pseudoepitheliomatous hyperplasia
38
Congenital Epulis occurrence/age//location?
rare, newborns, alveolar ridge
39
Congenital Epulis resembles?
Granular cell tumor
40
Congenital Epulis gender predilection %
90% female
41
Congenital Epulis histopath features similar to ? Exception?
Similar to granular cell tumor (abundant pale eosinophilic granular cytoplasm) but NO pseudoepitheliomatous hyperplasia
42
Most common peripheral nerve tumor?
Neurofibroma
43
Neurofibroma differentiation/histopath?
schwann/perineural cells, wavy nuclei, mast cells
44
Neurofibromatosis how many forms? Most common?
8, Type 1 most common (90%)
45
Neurofibromatosis causes what disease? Genetic source?
von Reck, autosomal dominant chromosome 17
46
Neurofibromatosis clinical features
multiple neurofibromas on skin, oral Cafe au lait pigmentation - smooth macules Crowe sign - freckles on axilla Lisch Nodules - brown pigmentation on iris
47
Oral manifestation of Neurofibromatosis?
50% enlarged fungiform papillae
48
Schwannoma most common oral site?
tongue
49
Schwannoma histopath features
encapsulated tumor
50
Schwannoma 2 patterns?
Antoni Pattern A - streaming fascicles of spindle Schwann cells palisaded around acellular Veroclay bodies Antoni Pattern B - random spindle cells in loose myxomatous stroma
51
Traumatic Neuroma happens why
transection or damage of nerve bundle leads to proliferation of neural tissue
52
Multiple Endocrine Neoplasia - genetic passing?
autosomal dominant
53
MEN Type 2 - three subtypes
Familial medullary thyroid carcinoma syndrome MEN Type 2A MEN Type 2B
54
MEN Type 2A - conditions (3)
Medullary carcinoma of thyroid (MCT) 95% pheochromocytoma of adrenal medulla 50% parathyroid hyperplasia/adenoma 25%
55
MEN Type 2B - How related to type 2A?
same conditions + multiple mucosal neuromas
56
MEN Type 2B clinical features?
Mucosal neuromas on eyes Oral neuromas - painless papules on lips and anterior tongue. MCT - ALMOST ALL PATIETNS, aggressive and metastatic, requires prophylactic thyroidectomy before age 1
57
MEN Type 2B first sign of disease?
Oral neuromas
58
MCT lab values
elevated serum/urinary calcitonin
59
pheochyromocytomas lab values
urinary vanillylmandelic acid (VMA) and increase epi to norepi ratio
60
Most common tumor of children
hemangioma of infancy
61
Evolution of hemangioma of infancy?
proliferate 6-10 months before involution
62
Vascular malformations happen when?
present at birth, persist
63
Lymphatic malformation most common site? | Surface?
65% in head/neck region Most common on anterior tongue Pebbly
64
Lymphatic malformation histopath?
proliferation of lymphatic vessels, valves