Beta-lactam Penicillins (-cillin) Flashcards

1
Q

Examples

A

Benzylpenicillin
Flucloxacillin
Amoxicillin
Piperacillin

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2
Q

MoA

A

Penicillin-binding protein
Inhibitor
Inhibits transpeptidase enzyme activity
Prevent catalysis of NAMA-NAG peptide cross-linking during cell wall formation
Inactivation of inhibitor of autolytic enzymes in cell wall

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3
Q

Indications

A

Streptococci

Staphylococci

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4
Q

ADR

A

Hypersensitivity, Anaphylaxis
Amoxicillin = otitis media, lyme
Encephalopathy

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5
Q

Prescribing Advice

A

Combined with B-lacatamase inhibitors

Co-amoxiclav/Tazocin

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