BI203 Ch. 24 - Online Quiz (MC) Flashcards
(12 cards)
Which of the following diseases would not be an ideal target for therapeutic cloning?
HIV
Which of the following products would result from caspase cleavage of a protein with the amino acid sequence AVEELCSTWYYDLLCHMRTL?
AVEELCSTWYYD + LLCHMRTL
The PI 3-kinase pathway activates Akt, which does ___ activate Bad.
NOT
The cloned embryo in somatic cell nuclear transfer is ___ genetically identical to the foster mother.
NOT
Apoptosis, or programmed cell death, occurs in all of the following cases except in ___ ___ ___.
cells damaged by injury
The following is a signal transduction cascade (with one missing step) initiated by double-stranded DNA damage and ending with activation of apoptosis by the BH3-only proteins PUMA and Noxa: Double-stranded DNA damage; Chk2; ___; PUMA/Noxa; apoptosis. Which protein belongs in the blank space?
p53
TNF binds a trimeric receptor complex on the surface of the cell membrane.
Upon receptor binding, ___ is activated through an adaptor protein.
___ then activates ___, which in turn activates Bax and Bak and then feeds into the mitochondrial pathway.
Caspase-8, Bid
Murine embryonic stem cells are grown in the presence of a growth factor. What growth factor is generally used for this?
LIF (Leukemia Inhibitory Factor)
___ is used to stimulate growth of fibroblasts.
PDGF (platelet-derived growth factor)
Tumors are ___ considered viable stem cells.
NOT
What is the best rationale for the use of therapeutic cloning to replace defective cells or tissues in a patient?
The transplanted cells are ___ to those of the recipient who donated the adult nucleus, so complications of immune rejection are ___.
identical, avoided
When activated, Bax and Bak form oligomers in the outer membrane of mitochondria, leading to the release of ___ ___.
cytochrome c
