Biliary disease Flashcards

1
Q

Asymptomatic gallstone in the gallbladder is called

A

Cholethiasis

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2
Q

3 factors that cause increased gallstone disease with age

A

1) decreased response to CCK
2) decreased motility
3) cholesterol saturation

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3
Q

Risk factors for gallstone disease

A

Family Hx
Obesity
Age
gender and hormones

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4
Q

Multiple pregnancy and high estrogen levels

A

increases risk of gallstones

- more cholesterol

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5
Q

If gallstone blocks the gallbladder duct and walls become irritated

A

acute cholecystisis

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6
Q

If the stone gets lodged in the CBD

A

Choledocholithiasis unless with infection -

ascending cholangitis

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7
Q

If stone gets blocked at the pancreatic duct

A

Pancreatitis

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8
Q

Constant RUQ due to cystic duct obstruction and distention of the GB - up to 24 hours

A

biliary colic

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9
Q

Treatment of biliary colic

A

IV fluids
analgesic
Elective cholecystectomy

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10
Q

3 bacteria that cause cholecystisis

A

E coli
Klebsiella
Enterococcus

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11
Q

acute cholecystisis is

A

biliary colic > 24 hours

  • fever
  • tachycardia
  • leukocytosis
  • positive murphy’s sign
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12
Q

How do you confirm the diagnosis of acute cholecystisis

A

Ultrasound

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13
Q

3 things you must get from anyone with upper abdo pain

A
  • ECG
  • Lipase
  • CXR
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14
Q

treating acute cholecystisis

A
  • Abx
  • IV fluids
  • Analgesics
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15
Q

What is ERCP used for

A

diagnosis and treatment of CBD stones

NOT gall bladder stones

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16
Q

MRCP is used for

A

Diagnosis of CBD stones

NOT gall bladder stones

17
Q

complications of gallstones related to the GB

A
  • acute cholecystisis
  • carcinoma
  • perforation
  • gallstone ileus
18
Q

complications of gallstones related to the Common bile duct

A
  • obstructive jaundice
  • cholangitis
  • pancreatitis
19
Q

Systemic complication of ascending cholangitis

A

Septic shock/bacteremia

20
Q

Charcot’s triad

A

Jaundice
Fever
RUQ

21
Q

Raynaud’s pentad

A
- jaundice
fever
RUQ
hypotensive
confusion
22
Q

IN acute pancreatitis what function of the pancreas are we referring to?

A

Exocrine functions

23
Q

Prognosis in Acute Pancreatitis

A

3-5% mortality

24
Q

2 most common causes of pancreatitis

A
alcohol
gall stones
post- ERCP
- cardiac sx 
CF
25
Q

2 mechanisms for drug-induced pancreatitis

A
  • immunolog-mediated allergic reaction
    early onset
  • chronic tox metabolite accumulation
  • late
26
Q

patient with pancreatitis

A

leaning forward from retroperitoneal pain

27
Q

Most specific and sensitive test for AP

A
  • lipase!
28
Q

Systemic effects associated with pancreatitis

A
- capillaries/vein 
coagulation pathways
white cells
blood vessels 
DIC
29
Q

Imaging findings in acute pancreatitis

A

colon cut off sign

30
Q

Most common form of organ failure from pancreas is

A

Renal

31
Q

Treament of pancreatitis is

A
Fluids
pain relief 
respiratory support
nutrition
ERCP