bio Flashcards

1
Q

Central Dogma

A

The genetic information flows from DNA to RNA to protein

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2
Q

Centromere

A

It is a region of DNA found near the middle of a chromosome where two identical sister chromatids come in contact.

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3
Q

Chromosome

A

is the thread-like structure that packages and organizes the DNA around proteins called histones.

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4
Q

Chromatid

A

one-half of two identical copies of a replicated chromosome joined by a single centromere and separated during cell division to become individual chromosomes at anaphase

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5
Q

Euchromatin

A

loosely packed chromatin that is easily accessible by transcription enzymes and actively transcribed

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6
Q

Heterochromatin

A

tightly packed chromatin that is not actively transcribed.

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7
Q

Denaturation

A

The separation of the two strands of DNA without breaking the major bonds of its chain

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8
Q

Exons

A

The protein-coding DNA sequences of a gene

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9
Q

Gene

A

an ordered sequence of nucleotides located in a particular position on a particular chromosome that encodes a specific functional product (protein or RNA)

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10
Q

Genome

A

All the genetic material in the chromosomes of a particular organism; its size is generally given as its total number of base pairs

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11
Q

Histone

A

A type of basic protein that packed long DNA molecules into a nucleus

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12
Q

Intron

A

DNA base sequence within a gene that is not translated into protein

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13
Q

Linker DNA

A

is a double-stranded DNA between two nucleosome cores

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14
Q

Melting temperature (Tm)

A

The temperature at which the two strands of DNA are dissociated

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15
Q

Noncoding DNA

A

DNA segments that do not contain instructions for making proteins

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16
Q

Nucleosome

A

a segment of DNA wrapped around a set of eight histone proteins which are known as a histone octamer. Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4

17
Q

Nucleotide

A

It is the building block (monomer) of nucleic acid which consists of three components: pentose sugar (ribose or deoxyribose), nitrogen base (purine or pyrimidine), and a phosphate group

18
Q

Nitrogenous base

A

A nitrogen-containing molecule having the chemical properties of a base

19
Q

Nucleic acid

A

A large molecule composed of nucleotide subunits

20
Q

Purine

A

A type of double-ring base (Adenine and Guanine)

21
Q

Pyrimidine

A

A type of single-ring base (Cytosine, Thymine, Uracil)

22
Q

Renaturation

A

The inverse process of denaturation where complementary strands of nucleic acids return to their original form

23
Q

Promoter

A

a region of DNA where RNA polymerase and other proteins bind directly to facilitate the transcription of a particular gene

24
Q

Operator

A

the region between the promoter and the first gene act as an “on-off switch”, it is the DNA binding site of the repressor protein

25
Operon
refers to a group of closely linked genes, arranged under a common promoter and regulated by a common operator whose mRNA is synthesized in one piece, which together codes for various enzymes of a particular biochemical pathway
26
Solenoid Structure
The packed arrangement of DNA in eukaryotic produced by coiling the continuous string of nucleosomes
27
Supercoil
A closed double-stranded circular DNA molecule that is twisted on itself in prokaryotes
28
Telomere
It is a region of repetitive DNA at the ends of chromosomes that protects the end of the chromosome from destruction
29
Telomerase
Enzymes that add a telomere repeat sequence to the 3' end of the telomere and make sure that the lagging strand is completed correctly at the terminal ends
30
Topoisomerase
Enzyme that can wind and unwind the tightly coiled DNA to control the synthesis of proteins
31
Transcription
process in which one DNA strand is used as a template to synthesize a complementary RNA
32
Transcription factor
a protein that binds to specific DNA sequences and controls the transcription of genetic information from DNA to mRNA