bio Flashcards
Central Dogma
The genetic information flows from DNA to RNA to protein
Centromere
It is a region of DNA found near the middle of a chromosome where two identical sister chromatids come in contact.
Chromosome
is the thread-like structure that packages and organizes the DNA around proteins called histones.
Chromatid
one-half of two identical copies of a replicated chromosome joined by a single centromere and separated during cell division to become individual chromosomes at anaphase
Euchromatin
loosely packed chromatin that is easily accessible by transcription enzymes and actively transcribed
Heterochromatin
tightly packed chromatin that is not actively transcribed.
Denaturation
The separation of the two strands of DNA without breaking the major bonds of its chain
Exons
The protein-coding DNA sequences of a gene
Gene
an ordered sequence of nucleotides located in a particular position on a particular chromosome that encodes a specific functional product (protein or RNA)
Genome
All the genetic material in the chromosomes of a particular organism; its size is generally given as its total number of base pairs
Histone
A type of basic protein that packed long DNA molecules into a nucleus
Intron
DNA base sequence within a gene that is not translated into protein
Linker DNA
is a double-stranded DNA between two nucleosome cores
Melting temperature (Tm)
The temperature at which the two strands of DNA are dissociated
Noncoding DNA
DNA segments that do not contain instructions for making proteins
Nucleosome
a segment of DNA wrapped around a set of eight histone proteins which are known as a histone octamer. Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4
Nucleotide
It is the building block (monomer) of nucleic acid which consists of three components: pentose sugar (ribose or deoxyribose), nitrogen base (purine or pyrimidine), and a phosphate group
Nitrogenous base
A nitrogen-containing molecule having the chemical properties of a base
Nucleic acid
A large molecule composed of nucleotide subunits
Purine
A type of double-ring base (Adenine and Guanine)
Pyrimidine
A type of single-ring base (Cytosine, Thymine, Uracil)
Renaturation
The inverse process of denaturation where complementary strands of nucleic acids return to their original form
Promoter
a region of DNA where RNA polymerase and other proteins bind directly to facilitate the transcription of a particular gene
Operator
the region between the promoter and the first gene act as an “on-off switch”, it is the DNA binding site of the repressor protein