BIOC 1 Flashcards
(15 cards)
gene
DNA information unit that is able to perform a function.
control region
determines if gene is On/Off
exon
protein coding and UTR
introns
splice acceptor and donor sites
splicing
carried out by protein complex= splice some
alternative spicing
away of making different proteins from 1 gene
non coding genes
- tRNA
- ribosomal RNA
- microRNA
nucleosome
DNA+ histone proteins
scaffold
topoisomerase ii
specific proteins
paradox
- 2 opposite functions (occurs stimultanseouly)
- DNA= stable to compact structure/protect from damage.
histone tails
- DNA wrapped around- proteins sticking out
- modification decides if it s complicated or not
substrata requirement for DNA polymerase
1-template
2-primer
3-a 3’OH end
prokaryotic DNA replication
a) DNA polymerases
b) replication initiation requires helicases and primase
c) the leading and lagging strand are synthesized simultaneously
d) replication terminates at specific sites
e) DNA is replicated with high fidelity
palm domain
- B sheets
- bind two Mg++ ions and specific amino acid chain
- monitors accuracy
- primary elements of catalytic site
fingers
- binds to incoming dNTPS
- fold over if correct base pair is made
- twist template so that only one base in the active site