Bioch Flashcards

1
Q

A.A à chaîne latéral polaire neutre : hydrophile ?

A

Glutamine (Gln,Q) cysteine (Cys,C) threonine (Thr,T) Tyrosine (Tyr,Y)
Serine (Ser,S) Asparagine (Asn,N)

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2
Q

A.A à chaîne latéral apolaire ? Hydrophobe

A

Glycine (Gly,G) ; Valine(Val,V) ; Alanine (Ala,A) ; Phenylalanine (Phe, F) ; Isoleucine (Ile,I) Leucine (Leu, L) ; proline (Pro,P) ; Methionine (Met, M) ; Tryptophan (Trp;W)

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3
Q

A.A à chaîne latéral polaire et ionisable ? Hydrophile

A

Aspartate (Asp,D) ; Glutamate (Glu,G) ; Lysine (Lys,K) ; Arguinine (Arg, R) ; Histidine (His,H)

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4
Q

Le brin matrice de l’ARNm est le brin anti sens ?

A

Oui

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5
Q

Quel ARN polymerase produit ARNm ?

A

ARN polymerase II

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6
Q

2 premières bases intron ?

A

GU

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7
Q

Plusieurs triplets codent le même acide aminé sauf ?

A

Met, Trp

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8
Q

Transition

A

Purique -> purique

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9
Q

Transversion

A

Purique -> pyrimidique

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10
Q

Purine

A

Adénine guanine

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11
Q

Pyrimidine

A

Thymine cytosine

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12
Q

Codon initiateur ?

A

AUG -> methionine

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13
Q

Codons STOP?

A

UAG UAA UGA

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14
Q

Parmi ARN polymérase II, Primase, Hélicase, PolyA polymérase, Ligase lequel dépendants de la séquence de l’ADN matrice ?

A

ARN polym II, Primase

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15
Q

Procaryotes cb ARN polym?

A

1

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16
Q

ADN mitochondrial ?

A

Bicatenaire, circulaire, non compacté, non associé aux histones

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17
Q

Réplication ADN?

A

Semiconservative , bidirectionnel

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18
Q

ADN polymerase ?

A

ADN polymerase, ADN dépendante

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19
Q

Cb ADN polymerase procaryotes ?

A

ADN POLYM I(brin tardif), ADN POLYM II(réparation) ADN POLYM III( brin direct)

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20
Q

Cb ADN POLYM chez eucaryotes ?

A

5 principaux sur 26

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21
Q

Primase ?

A

ARN POLYM ADN DÉPENDANTE
amorce ARN

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22
Q

Telomerase ?

A

ADN POLYM ARN DÉPENDANTE

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23
Q

CB ARNr?

A

4 : 28S, 18,5,8,5

24
Q

Synthèse ARNm ?

A

Recopiage du brin ADN matrice ou brin antisens

25
ARN POLYM?
ARN POLYM ADN DÉPENDANTE
26
ARN POLYM procaryotes ?
1
27
ARN POLYM eucaryotes ?
3
28
ARN POLYM I
Arnr (5,8 18,28)
29
ARN polym II
ARNm
30
ARN polymerase III?
Arnr 5S, Arnt
31
ARNm prématuré -> ARNm mature ?
Coiffe + queue polyadenylee + Exscision intron
32
2 dernière bases introns ?
AG
33
Glycine
(GLY,G) R: un H -> Calpha non asymétrique
34
Isoleucine
(Ile,I) R: 2e carbone asymétrique
35
Phenylalanine, tryptophane
(Phe,F) (Trp,W) R: absorbe 280nm Chaîne aromatique
36
AA fonction alcool ?
Serine (Ser,S) threonine (Thr,T)R: 2e carbone asymétrique tyrosine (Tyr,Y)R: aromatique 280nm R: phosphorylable -> active Prot
37
Fonction soufrée
Cysteine (Cys,C) Pont disulfure
38
AA fonction amide ?
Glutamine (Gln,Q) Asparguine (Asn,N)
39
AA Fonction acide ?
(Glu,E) (Asp,D) Négatif à pH 7,4
40
AA fonction basique ?
(His,H) neutre ph7,4 (Lys,K) (Arg,R) positif ph7,4
41
Structure primaire AA liaison peptidique?
Liaison covalente, plane rigide polaire Conformation trans plus stable
42
Hélice alpha Prot ?
Structure secondaire Riche alanine Pauvre glycine et proline
43
Structure secondaire type de liaison ?
Liaison hydrogène !
44
Feuillet Bêta Prot ?
Structure secondaire Pauvre en glycine et proline Riche valine phenylalanine, Tyrosine
45
Coudes boucle Prot ?
Structure secondaire non reguliaires et non répétitive. Riche glycine proline
46
Structure quaternaire ( assemblage monomère) : Prot?
Le plus souvent non covalent
47
Structure quaternaire Collagène ?
Riche glycine et proline, 2 AA inhabituelle : hydroxyproline et hydroxylysine.
48
Oxyhémoglobine ?
État relâché appelé R
49
Chymotripsine ?
Trp,Tyr,Phe
50
Trypsine ?
His
51
Homodimere ?
Deux même sous unité
52
Epissage alternatif ?
Exon élimine chez eucaryote
53
Amine df ?
1
54
Nitrile df ?
Df=3
55
Df amide ?
Df= 4
56
Df en fonction oxydation et réduction ?
Df monte avec oxydation et baisse avec réduction