Biochem

Question 1

High serum lvl of alaine aminotranferase indicates only liver damage

Answer 1

F

Question 2

Aminotranferase reactions are irreversible

Answer 2

F

Question 3

Aminotranferase requires pyrodoxal phosphate a co factor derived from B6

Answer 3

True

Question 4

Co factor of aminotranferase is attached to the enzyme via amide bond

Answer 4

F

Question 5

Glutamine is the most common product of aminotranferase reactions

Answer 5

F

Question 6

Choose amino acid used for protein synthesis but can’t be for humans except by metabolism of another amino acid which is impossible in normal metabolitoes

Answer 6

Tyrosine and cysteine

Question 7

2 nitrogens in urea enter urea synthesis pathway in what molecular form

Answer 7

One as amonia and one as alpha amino group of aspartate

Question 8

Person with phenylketonuria consumes food with high phenylalanine leads to

Answer 8

Phenylpyruvate

Question 9

Oxidation of fatty acids is highest between meals and lower in well fed states

Answer 9

True

Question 10

What is bilirubin conjugated with in jaundice

Answer 10

Glucuronic acid

Question 11

Carbs are beneficial because food with sugar tastes better

Answer 11

F

Question 12

Carbs are required for fat oxidation

Answer 12

F

Question 13

Carbs prevent hypoglycemia

Answer 13

T

Question 14

Carbs improve renal functions

Answer 14

F

Question 15

Carbs improve urea synthesis in the liver

Answer 15

F

Question 16

Nitric oxide and urea have in common this amino a id which is used as an immediate precursor

Answer 16

Arginine

Question 17

Which of the following incorrectly pairs a pathway with one of it’s regulated enzymes

Answer 17

Urea cycle carbamoyl phosphate synthetase ll CPS II

Question 18

Glucogenesis: which of the following incorrectly pairs a glycotic enzyme with the glucogenic enzyme that catalizes the reverse

Answer 18

Pyruvate kinase pyruvate dehydrogenase (turns pyruvate to acetylcoa)

Question 19

Which one is the precursor of potent vasoconstrictor serotonin

Answer 19

Tryptophan

Question 20

Which of the following essential dietary factors is a precursor for a compound as a carrier of the acetate group (two-carbon fragment)?
A. Methionine
B. Thiamine
C. Folic acid
D. Biotin
E. Pryidoxine

Answer 20

Thiamine

Question 21

Choose the wrong statement in the transamination of amino acids.
A. Pyridoxal phosphate is a cofactor
(B) The reaction is tightly controlled by allosterie effectors
© The amino group acceptor is typically an a-keto acid alpha keto glutarate
D. Ammonia is neither consumed nor produced
E. Proline is one of few amino acids which are not subjected to transamination

Answer 21

(B) The reaction is tightly controlled by allosterie effectors

Question 22

Which one of the following amine acids is purely Ketogenic regarding the fate of carbon skeletons?
A. Isoleucine
B. Tyrosine
C. Alanine
D.Leucine
E. Gycine

Answer 22

(D? Leucine

Question 23

28. Choose the wrong statement regarding the digestion of proteins?
    A. Pepsinogen is activated by autoactivation (pH 2) or autocatalysis
    B. The major products of peptic hydrolysis are mostly large peptides
    C. Trypsin and chymotrypsin are secreted by the pancreas as inactive zymogens
    D. Enteropeptidase (enterokinase) activates pancreatic trypsinogen
    dipeptides / small
    Most of the digested proteins are absorbed in the intestines in the form of polypeptides

Answer 23

Most of the digested proteins are absorbed in the intestines in the form of polypeptides

Question 24

Which enzymatic activity in the pentose phosphate pathway requires thiamine pyrophosphate (TPP) as a cofactor?
A. Glucose 6-phophate dehydrogenase (G6PD)
B. 6-Phosphogluconate dehydrogenase
C.Transketolase
D. Transaldolase
E. Phosphopentose isomerase

Answer 24

Transketolase

Question 25

Which polysaccharide cannot be hydrolysed by humans due to the presence ofthep finkage in repeating units? A. Amylopectin B. cellulose D. Starch E. Glycogen

Answer 25

Cellulose

Question 26

A protein X is formed by two chains with 80 amino acids in one chain and 58 in the other. These two chains are linked by disulfide bonds and all the essential amino acids are present in the structure. but not all the non-essential amino acids. With this information, how can you classify this protein according to the nutritional value? A. A globular protein B. A fibrous protein C. A conjugated protein D. An incomplete protein E.A complete protein

Answer 26

(E) A complete protein

Question 27

3. An amino acid that yieldsfacetoacetyl Co/ during the catabolism of its carbon skeleton would be considered as one of the following. Choose the correct answer. A. Glycogenic B. Ketogenic C. Glycogenic and ketogenic D. Neither glycogenic nor ketogenic E. Essential

Answer 27

Ketogenic

Question 28

ketogenic and glucogenic that yield acetoacety

Answer 28

tryptophan, phenylalanine, tyrosine

Question 29

4. Which carriers are used to transport the NH, produced in muscle degradation of nitrogenated compounds through blood to the liver? A. Alanine and glutamine B. Urea and alanine C. NH: and glutamate D. Glutamate and glutamine E. a-Ketoglutarate and urea

Answer 29

Alanine and glutamine

Question 30

5. Choose the correct answer for the necessary coenzyme for transmination reactions A.Prridoxal phosphate B. Thiamine pyrophosphate C.Coenzyme A D. Tetrahydrobiopterin E. Folate

Answer 30

Prridoxal phosphate

Question 31

Amino acids are requared for the syntheses of other nitrogen compoundse

Answer 31

T

Question 32

Essential amino scads must be obtained in the diet daily.

Answer 32

T

Question 33

Nitrogen is continuously lost from the body regard less of the protein intake amount

Answer 33

T

Question 34

.... proteins have the highest biological value

Answer 34

Animal origin

Question 35

Protein degradation to provide energy results in

Answer 35

Loss of other functions

Question 36

The carbon atoms of serine can, appear in all of the following except one of them. Indicate which ore is that? A. Pyruvite B.leucine C.glycine D.sphyngomylin Ephosphatidyl ethanolamine

Answer 36

sphyngomylin

Question 37

Which of the following is an intermediate in the degradation of lysine?

Answer 37

Seccharopine

Question 38

All amino acids are glucogenic.

Answer 38

F

Question 39

Amino acid catabolisen is increased during...

Answer 39

Starvation

Question 40

All amino acids are essential amino acids.

Answer 40

F

Question 41

The major excrctory end profact of acmino acid catabolism is

Answer 41

Urea

Question 42

Tissue proccin synthesis is decreased duting periods of growth.

Answer 42

F

Question 43

Besides diet restrictions, bat warranting an apocopriate amount of the essential amine aids, which of the following amino acids you should supelement in higher quantities than in a normal dict. since it is essential for a PRU (obenytectonuna) patient.

Answer 43

Tyrosine

Question 44

The diet must supply only enough phenylalanine and tyrosine to meet the needs for

Answer 44

protein synthesis.

Question 45

Which of the following is an example of the oxidative desination reaction taking part in amino acids metabolism

Answer 45

Glutamate = alpha-Ketoglunarate + NH3

Question 46

Glutamate=hexanoic acid+NH3

Answer 46

Glutamate dehydrogenase

Question 47

Pepsinogen us activated by

Answer 47

Auto activated ph2 Autocatalysis

Question 48

Major products of peptiv hydrolysis

Answer 48

Large peptides

Question 49

Trypsin amd chemotrypsin are secreted by... as...

Answer 49

Pancreas Inactive zygomens

Question 50

Enterokinase activates

Answer 50

Pancreatic trypsinogen

Question 51

..... is an amino acid not subjectted to transmination

Answer 51

Proline