biochem Flashcards

(39 cards)

1
Q

Edward buuchnar was famous for?

A

discovery of cell free fermentation

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2
Q

a carbon atom forms 4 bonds with a ______ arrangement?

A

tetrahedral

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3
Q

what are the 5 trace elements?

A

zinc, iron, manganeese, copper, cobalt

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4
Q

nucleotides are linked by _________ bonds?

A

phosphodiester bonds

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5
Q

polypeptides are?

A

covalently linked amino acids

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6
Q

amino acids are linked by ________ bonds?

A

peptide bonds

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7
Q

monosaccharides are linked by ______ bonds?

A

glycosidic bonds

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8
Q

name one way metabolic pathways are important

A
  • they enable cells to coordinate and control complex biochemical processes in response to available energy
  • they function with membrane bound cells
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9
Q

what are metabolites?

A

small biomolecules that serve both as reactants and products in biochemical reactions within cells

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10
Q

metabolic flux is?

A

the rate at which reactants and products are interconverted in a metabolic pathway

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11
Q

argininosuccinate synthetase and arginosuccinase are two enzymes involved in which metabolic reaction?

A

urea cycle

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12
Q

metabolic pathways can be linear, ______, or ________?

A

forked or cyclic

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13
Q

order from largest to smallest ( supramolecular complexes, monomeric units, macromolecules, the cell)

A

the cell
supramolecular complexes
macromolecules
monomeric units

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14
Q

who collected x ray diffraction data to determine the structure of dna?

A

rosalind franklin and maurice wilkins

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15
Q

erwin chargaff did what?

A

studied base composition of dna, used chromatography to quantify bases in dna

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16
Q

base composition does not change with age, nutritional state and the environment? (T or F)

17
Q

ratios of certain bases are fixed at ____:_____?

18
Q

Chargaffs rule is?

19
Q

who determined dna was a double helix?

A

watson and crick

20
Q

deoxyribonucleotides are? while ribonucleotides are?

A
  • mononumeric units of dna that lack an OH group on the c2 end of the ribose sugar
  • structurally similar but contain an OH group on the c2 end of the ribose sugar
21
Q

complementary base pairs are ?

22
Q

base pairs are held together by ___ bonds?

23
Q

there are ___ bonds in a GC pair but only ___ in a AT pair? (#)

24
Q

central dogma of molecular biology describes how?

A

information is transfered between dna rna and proteins

25
dna transcription involves _____ while translation involves _____?
mrna, proteins
26
genomes consist of _____ but in viruses they consist of _____?
dna , rna
27
a transcriptome is ?
set of all rna molecules in one cell or population of cells
28
a proteome is ?
entire set of proteins expressed by a genome, cell, tissue, or organism (set of expressed proteins)
29
can mutations be passed from parents to offspring?
yes in germ line cells
30
can mutations in somatic cells be passed to offspring?
no only in germ line cells
31
what type of reaction occurs during fermentation of acetaldehyde to ethanol in yeast?
redox
32
carbon bonding form bonds how?
covalent bonds with up to four atoms
33
based on chargaffs ratios the ____ of purine residues must _____ the ______ of the pyridamine residues
sum, equal, sum
34
4 major classes of biomolecules?
amino acids, nucleotides, simple sugars, fatty acids
35
what is paralogous?
homologous within a species, gene duplication
36
orthoologous is?
different species, gene and main function conserved
37
does delta g provide information about the rate of reaction?
no
38
under what condition will a reaction occur spontaneously ?
products more disordered than the reactants
39
what are the two unusual properties of water?
high boiling point and high melting point high heat capacity high latent heat and vapourization