biochem Flashcards

1
Q

Edward buuchnar was famous for?

A

discovery of cell free fermentation

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2
Q

a carbon atom forms 4 bonds with a ______ arrangement?

A

tetrahedral

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3
Q

what are the 5 trace elements?

A

zinc, iron, manganeese, copper, cobalt

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4
Q

nucleotides are linked by _________ bonds?

A

phosphodiester bonds

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5
Q

polypeptides are?

A

covalently linked amino acids

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6
Q

amino acids are linked by ________ bonds?

A

peptide bonds

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7
Q

monosaccharides are linked by ______ bonds?

A

glycosidic bonds

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8
Q

name one way metabolic pathways are important

A
  • they enable cells to coordinate and control complex biochemical processes in response to available energy
  • they function with membrane bound cells
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9
Q

what are metabolites?

A

small biomolecules that serve both as reactants and products in biochemical reactions within cells

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10
Q

metabolic flux is?

A

the rate at which reactants and products are interconverted in a metabolic pathway

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11
Q

argininosuccinate synthetase and arginosuccinase are two enzymes involved in which metabolic reaction?

A

urea cycle

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12
Q

metabolic pathways can be linear, ______, or ________?

A

forked or cyclic

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13
Q

order from largest to smallest ( supramolecular complexes, monomeric units, macromolecules, the cell)

A

the cell
supramolecular complexes
macromolecules
monomeric units

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14
Q

who collected x ray diffraction data to determine the structure of dna?

A

rosalind franklin and maurice wilkins

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15
Q

erwin chargaff did what?

A

studied base composition of dna, used chromatography to quantify bases in dna

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16
Q

base composition does not change with age, nutritional state and the environment? (T or F)

A

T

17
Q

ratios of certain bases are fixed at ____:_____?

A

1:1

18
Q

Chargaffs rule is?

A

A+G=T+C

19
Q

who determined dna was a double helix?

A

watson and crick

20
Q

deoxyribonucleotides are? while ribonucleotides are?

A
  • mononumeric units of dna that lack an OH group on the c2 end of the ribose sugar
  • structurally similar but contain an OH group on the c2 end of the ribose sugar
21
Q

complementary base pairs are ?

A

GC and AT

22
Q

base pairs are held together by ___ bonds?

A

H

23
Q

there are ___ bonds in a GC pair but only ___ in a AT pair? (#)

A

3, 2

24
Q

central dogma of molecular biology describes how?

A

information is transfered between dna rna and proteins

25
Q

dna transcription involves _____ while translation involves _____?

A

mrna, proteins

26
Q

genomes consist of _____ but in viruses they consist of _____?

A

dna , rna

27
Q

a transcriptome is ?

A

set of all rna molecules in one cell or population of cells

28
Q

a proteome is ?

A

entire set of proteins expressed by a genome, cell, tissue, or organism (set of expressed proteins)

29
Q

can mutations be passed from parents to offspring?

A

yes in germ line cells

30
Q

can mutations in somatic cells be passed to offspring?

A

no only in germ line cells

31
Q

what type of reaction occurs during fermentation of acetaldehyde to ethanol in yeast?

A

redox

32
Q

carbon bonding form bonds how?

A

covalent bonds with up to four atoms

33
Q

based on chargaffs ratios the ____ of purine residues must _____ the ______ of the pyridamine residues

A

sum, equal, sum

34
Q

4 major classes of biomolecules?

A

amino acids, nucleotides, simple sugars, fatty acids

35
Q

what is paralogous?

A

homologous within a species, gene duplication

36
Q

orthoologous is?

A

different species, gene and main function conserved

37
Q

does delta g provide information about the rate of reaction?

A

no

38
Q

under what condition will a reaction occur spontaneously ?

A

products more disordered than the reactants

39
Q

what are the two unusual properties of water?

A

high boiling point and high melting point
high heat capacity
high latent heat and vapourization