Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Board Review > BIOCHEM--Metabolism > Flashcards

BIOCHEM--Metabolism Flashcards

(54 cards)

Start Studying
1
Q

Where does Alcohol dehydrogenase turn ethanol into acetaldehyde?

A

in the cytosol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What enzyme converts EtOH→Acetaldehyde in the peroxisome?

A

Catalase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What enzyme converts EtOH→Acetaldehyde in the microsome?

A

CYP2E1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

MOA of Fomepizole

A

Inhibits alcohol dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What enzyme converts Acetaldehyde→Acetate

A

Acetaldehyde dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

MOA of Disulfiram

A

Inhibits acetaldehyde dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is an indication for Fomepizole?

A

Is an antidote For Overdoses of Methanol or Ethylene glycol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Accumulation of ___ causes hangover symptoms

A

acetaldehyde

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Where does Acetaldehyde dehydrogenase convert Acetaldehyde→Acetate?

A

mitochondria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the limiting reagent of EtOH metabolism?

A

NAD+

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What kind of kinetics does alcohol dehydrogenase have?

A

zero-order

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What (5) metabolic processes take place only in the mitochondria?

A
  1. TCA cycle
  2. Oxidative phosphorylation
  3. Fatty acid oxidation (β-oxidation)
  4. Acetyl-CoA production
  5. Ketogenesis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What (7) metabolic processes take place only in the cytoplasm?

A
  1. glycolysis
  2. HMP shunt
  3. Synthesis of steroids
  4. Synthesis of nucleotides
  5. Synthesis of proteins
  6. Synthesis of fatty acids
  7. Synthesis of cholesterol
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which (3) metabolic processes occur in both the mitochondria and the cytoplams?

A
  1. Heme Synthesis
  2. Urea Cycle
  3. Gluconeogenesis

“HUGS take 2 (both)”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Kinase

A

Catalyzes a transfer of a phosphate group from a high-energy molecule (usually ATP) to a substrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

phosphorylase

A

Adds inorganic phosphate onto a substrate w/o using ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Phosphatase

A

Removes phosphate group from substrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Dehydrogenase

A

Catalyses oxidation-reduction reactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Hydroxylase

A

Adds hydroxyl group (-OH) onto a substrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Carboxylase

A

Transfers CO2 groups w/ the help of biotin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Mutase

A

Relocates a functional group w/i a molecule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Synthase/Synthetase

Study These Flashcards
A

Joins two molecules together using a source of energy

23
Q

Rate Determining Enzyme: glycolysis

Study These Flashcards
A

Phosphofructokinase-1
(PFK-1)

24
Q

Rate Determining Enzyme: Gluconeogenesis

Study These Flashcards
A

Fructose-1,6-bisphophatase

25
Rate Determining Enzyme: TCA cycle
Isocitrate Dehydrogenase
26
Rate Determining Enzyme: Glycogenesis
Glycogen synthase
27
Rate Determining Enzyme: Glycogenolysis
Glycogen phosphorylase
28
Rate Determining Enzyme: HMP Shunt
Glucose-6-phosphate Dehydrogenase
 (G6PD)
29
Rate Determining Enzyme: De novo pyrimidine synthesis
Carbamoyl phosphate synthetase II
30
Rate Determining Enzyme: De novo purine synthesis
Glutamine-phosphoribosylpyrophosphate (PRPP) amidotransferase
31
Rate Determining Enzyme: urea cycle
Carbamoyl phosphate synthetase I
32
Rate Determining Enzyme: Fatty Acid synthesis
Acetyl-CoA carboxylase | 
(ACC)
33
Rate Determining Enzyme: fatty acid oxidation
Carnitine acyltransferase I
34
Rate Determining Enzyme: Ketogenesis
HMG-CoA synthase
35
Rate Determining Enzyme: cholesterol synthesis
HMG-CoA reductase
36
Regulators of PFK-1
AMP ⨁ Fructose-2,6-bisphosphate ⨁ ATP ⊖ Citrate ⊖
37
Regulators of Fructose-1,6-bisphophatase
Citrate ⨁ 
Fructose-2,6-bisphosphate ⊖
 AMP ⊖
38
Regulators of Isocitrate Dehydrogenase
ADP ⨁
 ATP ⊖
 NADH ⊖
39
Regulators of Glycogen synthase
``` Glucose-6-phosphate ⨁
 insulin ⨁ 
cortisol ⨁
 epinephrin ⊖
 glucagon ⊖ ```
40
Regulators of Glycogen phosphorylase
``` Epinephrin ⨁
 glucagon ⨁
 AMP ⨁ 
 Glucose-6-phophate ⊖
 insulin ⊖
 ATP ⊖ ```
41
Regulators of G6PD
NADP+ ⨁
 | NADPH ⊖
42
Regulators of Carbamoyl phosphate synthetase II
ATP ⨁ 
PRPP ⨁
 UTP ⊖
43
Regulators of Glutamine-phosphoribosylpyrophosphate (PRPP) amidotransferase
AMP ⊖
 inosine monophosphate (IMP) ⊖
 GMP ⊖
44
Regulators of Carbamoyl phosphate synthetase I
N-acetylglutamate ⨁
45
Regulators of ACC
Insulin ⨁
 citrate ⨁
 glucagon ⊖
 palmitoyl-CoA ⊖
46
Regulators of Carnitine acyltransferase I
Malonyl-CoA ⊖
47
Regulators of HMG-CoA synthase
none i guess
48
Regulators of HMG-CoA reductase
insulin ⨁
 thyroxine ⨁
 glucagon ⊖
 cholesterol ⊖
49
aerobic metabolism of 1 glucose molecule produces ___ ATP via the malate-aspartate shuttle
32
50
aerobic metabolism of 1 glucose molecule produces ___ ATP via the glycerol-3-phsophate shuttle
30
51
___ ___ only produces 2 net ATP per glucose molecule
anareobic glycolysis
52
What affect does arsenic have on glycolysis?
produce 0 net ATP
53
NAD+ used in ___ processes
catabolic
54
NADPH used in ___ processes
anabolic

Board Review (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions