Biochemistry Flashcards

1
Q

heat is supplied by the surroundings to the system of chemical reaction

A

endothermic process

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2
Q

heat generated by combustion process is transferred from the system of chemical reaction to surroundings

A

exothermic process

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3
Q

total energy attributed to particles of matter and their interactions within a system, composed of thermal energy and chemical energy

A

internal energy

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4
Q

occurs without loss or gain of energy by heat

A

adiabatic process

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5
Q

major organ controlling body temperature

A

hypothalamus

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6
Q

proton acceptors

A

base

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7
Q

all amino acids are chiral except for

A

glycine

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8
Q

refers to an amino acid which bear no net charge at the isoelectric pH

A

zwitterion

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9
Q

MSUD enzyme deficient

A

branched chain alpha keto acid dehydrogenase

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10
Q

PKU enzyme deficient

A

phenylalanine hydroxylase

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11
Q

precursor of phenylalanine

A

tyrosine

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12
Q

largest side chain

A

tryptophan

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13
Q

precursor of homocysteine and cysteine

A

methionine

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14
Q

treatment for sickle cell disease

A

hydroxyurea

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15
Q

most abundant protein in the body

A

collagen

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16
Q

most common form of collagen

A

type I

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17
Q

upward and outward dislocation of the lens

A

ectopia lentis

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18
Q

downward and inward dislocation of the lens

A

homocystinuria

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19
Q

seen in the urine of multiple myeloma patients

A

kappa and lambda chains (light chains)

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20
Q

most abundant organic molecules in nature

A

carbohydrates

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21
Q

sugar units are linked together by

A

glycosidic bonds

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22
Q

excreted in the urine in essential pentosuria

23
Q

nitrogenous base + pentose sugar + phosphate

A

nuclerotide

24
Q

nitrogenous base + pentose sugar

A

nucleoside

25
cortisol prevents hypoglycemia during
stress
26
glucagon prevents hypoglycemia during
fasting
27
most abundant free nucleotide in mammalian cell
ATP
28
chargaff's rule
purine = pyrimidine
29
protein coding RNA
mRNA
30
best indicator for wasting
weight-for-height/length
31
best indicator for stunting
height/length-for-age
32
use "length" until
2 years old - beyond that we use height
33
strongly correlated with various metabolic and disease outcomes
BMI
34
responsible for liver fibrosis
stellate cells of ito
35
responsible for liver regeneration
oval cells
36
most common vitamin deficiency worldwide
vitamin A
37
earliest sign of vitamin A deficiency
loss of sensitivity to green light
38
earliest symptom of vitamin A deificency
nyctalopia (night blindness)
39
follicular hyperkeratosis
phrynoderma or toad skin
40
acute toxicity in vitamin A
pseudotumor cerebri headache, vomiting, blurred vision, stupor (may be confused with brain tumor)
41
biologically active form of vitamin D
1-25-(OH)2-cholecalciferol (calcitriol)
42
inhibitor of calcium oxalate stone formation
nephrocalcin
43
what vitamin regulates calcium and phosphorus
vitamin D
44
major site of iron absorption
proximal duodenum
45
necrosis of cardiac muscle fibers
keshan cardiomyopathy
46
specialized group of proteins required for the proper folding of many species of proteins prevent aggregation of proteins
chaperone proteins
47
what molecules regulates the allosteric enzymes
effectors
48
major digestion in the small intestine
pancreatic amylase
49
hydrolyzes phospholipids
phospholipase A2
50
chromosome that contains HLA loci
chromosome 6
51
most common form of complement deficiency worldwide
C2
52
it is the transfer nad utilization of energy in biologic systems
bioenergetics
53