Thiamine Essential in thiamine pyrophosphate (TPP), cofactor for: - Pyruvate dehydrogenase (links glycolysis to TCA cycle) - a-ketoglutarate dehydrogenase (TCA cycle) - Transketolase (HMP shunt)

Biochemistry - Nutrition Flashcards by Siddharth Ninan

Vitamin A

Retinol

Antioxidant, constituent of visual pigment (retinal), essential for normal differentiation of epithelial into specialized tissue, prevents squamous metaplasia.

Found in liver & leafy vegetables

DEFICIENCY - Night blindness, dry skin

EXCESS - Symptoms of raised ICP, arthralgia, fatigue, headaches, sore throat, alopecia. Teratogenic

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Vitamin B1

Thiamine

Essential in thiamine pyrophosphate (TPP), cofactor for:

Pyruvate dehydrogenase (links glycolysis to TCA cycle)
a-ketoglutarate dehydrogenase (TCA cycle)
Transketolase (HMP shunt)

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Biochemistry - Nutrition Flashcards

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