Biolingo- cell membrane and extracellular membrane Flashcards

(40 cards)

1
Q

I am a nucleotide and I have ribose as a sugar. What am I?

A

RNA

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2
Q

What is the definition of Nucleoside?

A

A componant of a nucleotide that is composed of a sugar group (ribose or deoxyribose), and a nitrogenous base

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3
Q

True or False: A nucleoside is a nucleic acid monomer. It is composed of a sugar, a phosphate group and a nitrogenous base.

A

False. Nucleosides are composed of a sugar and a nitrogenous base but they do not have a phosphate group. In fact, nucleotides are the monomers of nucleic acid.

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4
Q

I am a protein that separates parental DNA strands during DNA replication. What am I?

A

Helicase

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5
Q

Which missense mutation in the active site of an enzyme is least likely to affect its enzymatic activity?

A

Valine, a nonpolar amino acid to Leucine, a nonpolar amino acid

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6
Q

Describe DNA.

A

A nucleotide polymer with a bidirectional structure carrying the genetic information of living organisms and some viruses.

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7
Q

I am a DNA fragment newly synthesized on the discontinuous strand. What am I?

A

Okazaki fragment

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8
Q

Complete the following sentence: Replication and transcription begin at specific sites on the chromosome. Replication starts at the ________ whereas transcription begins at the _________ after the promoter.

A

Origin ; Start site (TSS)

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9
Q

Which anticodons corresponds to the codon GUA?

A

CAU

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10
Q

Complete the following sentence: Often an _______ codes for a specific protein domain.

A

Exon

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11
Q

What am I? A type of mutation that can affect multiple genes.

A

Chromosomal rearrangement

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12
Q

What determines where transcription begins?

A

Promoter sequences on DNA

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13
Q

What am I? A protein that reduces the tension in the replication fork.

A

DNA gyrase

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14
Q

Which mechanisms regulate gene expression in eukaryotes?

A

Methylation of DNA; Activators and repressors that regulate the transcription of a gene; and Micro-RNAs that prevent the production of a particular protein

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15
Q

Example of a Watson-Crick base pair in DNA.

A

Adenine - Thymine; Guanine - Cytosine

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16
Q

Describes a genetic mutation.

A

Permanent modification to the genome of an organism

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17
Q

I am a protein that binds to a specific sequence of DNA in order to reduce the transcription of a specific gene. What am I?

18
Q

What will be added to the 5’ end of a mature messenger RNA?

19
Q

What am I? A point mutation that has no effect on the amino acid sequence of a protein.

A

Silent mutation

20
Q

Describe transfer RNA.

A

RNA that brings amino acids to ribosomes during protein synthesis.

21
Q

I am an enzyme that synthesizes ribosomal RNA.

A

RNA polymerase I

22
Q

I am a nucleotide and I have ribose as a sugar.

23
Q

True or False: Promoters are required for the initiation of transcription in eukaryotes and prokaryotes.

A

True, promoters are required in both domains. However their organization is very different between eukaryotes and prokaryotes.

24
Q

I am an enzyme that binds together Okazaki fragments.

25
How are metabolic pathways regulated in the long term?
By the expression of genes that code for the enzymes needed for this pathway.
26
I am an enzyme that synthesizes messenger RNA.
RNA polymerase II
27
I am a non-coding DNA sequence that protects DNA from shortening during replication/
Telomeres
28
I am a protein that binds to a specific sequence of DNA in order to stimulate the transcription of a specific gene.
Activator
29
Where are chaperone proteins mostly found?
Golgi apparatus and cytoplasm
30
What is a replication model of DNA where parent strands each associate with a new complementary strand.
Semi-conservative model
31
Glycosylation is a potential protein modification in eukaryotes.when does this modification take place?
Post-translation
32
What is an aromatic compound that pairs with a purine to form the double alpha helix of DNA.
Pyrimidine
33
What is composed of a modified guanine and a methyl group attached to the 5’ extremity of mRNAs?
5’ cap
34
What is the step in the dogma of molecular biology in which mRNA is used as a matrix to synthesize proteins?
Translation
35
DNA has a ____ structure that protects stabilizes it.
Helicoidal
36
The central dogma involves _____.
replication, transcription, and translation
37
In the _____ transport vesicles continuously leave the Golgi apparatus to guise with the plasma membrane.
Constitutive secretory pathway
38
What is an epigenetic process resulting in the addition of a methyl group to a cytosine.
DNA methylation
39
During translation, _____________ reads an mRNA molecule and assembles the polypeptides to form proteins according to the sequence read on the mRNA.
Ribosome
40
Explain the difference between the synthesis of a leading strand and a lagging strand.
During synthesis, DNA polymerase can only add nucleotides at the 3' end of the new strands.