Biological Exp Genetic

Question 1

What is the genetic explanation of SZ about?

Answer 1

SZ is inherited through genes and passed down in families

Question 2

There is evidence that the ……. the biological relationship the ………………. greater the risk of SZ developing.

Answer 2

Closer
Greater the risk

Question 3

For first degree relatives (offspring, parents, siblings) they share……. of dna

Answer 3

50%

Question 4

Gottesman looked at heritability of SZ. What did the graph show for parents, siblings and twins?

Answer 4

Parents- 6%
Siblings- 9%
Fraternal twins- 17%
Identical twins- 48%

Question 5

What are concordance rates?

Answer 5

The rate of probability that 2 people that share the same genes will get the same organic disease

Question 6

What did gotten results suggest about genetics as an explanation of SZ?

Answer 6

Suggest that there is some genetic explanation for SZ. As the closer genetic relation to someone that has SZ increases your risk of developing SZ due to higher concordance rate

Question 7

Twin studies
Cardno et al
Found 40% of concordance rate in MZ twins compared with 5.3% in DZ twins. What does this suggest about genetics as an explanation of SZ?

Answer 7

Some genetic explanation
Closer genetic relationship= higher risk of developing SZ. Seen in MZ concordance being higher than DZ twins.

Question 8

Adoption study
Heston
Compared 47 children children of schizophrenic mothers who were adopted into non-SZ families, before the age of one month, with a control group of 47 children (with no bio SZ mother) raised by non-SZ families.
10% of the children with SZ mothers developed it later whereas 0 of the children from the control group did.
What does this suggest about genetics as an explanation of SZ?

Answer 8

Some genetic influence
Hit concordat results aren’t high so also shows support for there being some other influence