Biological Explanation for Schizophrenia Flashcards

(12 cards)

1
Q

What is the core idea of the genetic explanation for schizophrenia?

A

The genetic explanation suggests that schizophrenia is inherited and therefore tends to run in families.

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2
Q

What is the concordance rate for monozygotic (MZ) twins regarding schizophrenia?

A

MZ twins have a 48% concordance rate.

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3
Q

What is the concordance rate for dizygotic (DZ) twins regarding schizophrenia?

A

DZ twins have a 17% concordance rate.

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4
Q

How does the risk of schizophrenia in the general population compare to twins?

A

The risk in the general population is 1%, which supports the idea that sharing genes increases risk.

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5
Q

What does it mean that schizophrenia is polygenic?

A

Schizophrenia is influenced by many genes, each contributing a small increase in risk.

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6
Q

What is the link between schizophrenia and dopamine regulation?

A

Many genes associated with schizophrenia are linked to dopamine regulation, explaining abnormal dopamine activity in affected individuals.

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7
Q

What does genetic variability mean in the context of schizophrenia?

A

Different individuals with schizophrenia may carry different combinations of risk genes.

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8
Q

What supporting evidence exists for the genetic explanation of schizophrenia?

A

Children born to biological parents with schizophrenia are more likely to develop the disorder, even when adopted into families with no history of schizophrenia.

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9
Q

What is a limitation regarding confounding variables in twin studies?

A

MZ twins might have higher concordance rates due to shared environments, not just genetics.

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10
Q

What is the concern with biological determinism in the genetic explanation?

A

It suggests people are predetermined to develop schizophrenia due to their genes, potentially leading to feelings of hopelessness.

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11
Q

What is a limitation of biological reductionism in the genetic explanation?

A

It reduces schizophrenia to just a genetic cause, ignoring psychological and environmental factors.

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12
Q

What alternative model provides a more holistic view of schizophrenia?

A

The diathesis-stress model suggests schizophrenia develops from an interaction between genetic vulnerability and environmental stressors.

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