Biological membranes + Cell DDD Flashcards
(111 cards)
What is the function of a cell memebrane
membranes form barriers and separate the cell contents from the cells exterior environment. Or separate organelles from the cytoplasm, they need to allow some molecules through, into or out of the cell. So some membranes also have permeability.
What is permeability
Permeability refers to the ability to let substances pass through. Some very small molecules simply diffuse through the cell membrane, in its structural molecules. Some substances dissolve in the lipid layer and simply pass through. And finally some substances pass through through special protein channels or carriers.
What type of permeability do plasma cell membranes have and why ?
Partially permeable- only allow some substances through. The properties of the membranes components determines its permeability. For example how many proteins it contains, ect.
What is the role of membranes at the surface of cells
The plasma membrane: separates the cells components from its external environment (in single celled organisms the environment is its external environment) the membrane regulates the transport of materials in and out of the cell. It may also contain enzymes involved in many metabolic pathways. They also have antigens so that the organisms immune system can recognise the cell as self and not attack it. Finally, membranes may release chemicals to other cells.
What is the role of membranes within cells
The membranes found around organelles in eukaryotic organisms separate the cell contents from the cytoplasm so each organelle is its own discrete entity. For example, mitochondria have a folded inner membrane called cristae, this gives large surface areas for the reactions of aerobic respiration.
As well as this, chloroplasts have inner membranes called thylakoids, which house chlorophyll. On these membranes stages of photosynthesis occurs.
State the fluid mosaic model of cell membrane structure
In 1972, singer and Nicholson proposed a model that allowed the passage of molecules through the membrane. Their structure explained how membranes could be more dynamic and interact more with the cells environment. It was called the fluid mosaic model. And proposed that the fabric of the membrane consisted of a phospholipid bi-layer. With proteins embedded floating within it, making up a mosaic pattern. The lipid molecules can change places with each other, and some proteins move giving it more fluidity. The fabric of the membrane, made out of the lipid bilayer, have their hydrophilic polar heads on contact with the water exterior and interior of the cell. The hydrophobic tails are then tucked away inside the membrane.
State and Describe the various proteins involved within membranes
Some of the proteins have pores and act as channels to allow ions, which have an electrical charge and are surrounded by water molecules, to pass through.
Some of the proteins are carriers and, by changing their shape, carry specific molecules across the membrane.
And finally, other proteins may be attached to the carrier proteins and function as enzymes, antigens or receptor sites for complementary-shaped signalling molecules such as hormones.
What is the function of cholesterol in membranes
The function of cholesterol in the cell membrane is to stabilize the interactions between the phospholipids and prevent the membrane from getting too fluid or too flexible. It also resists temperature changes on the structure of the membrane.
What is the total thickness of the cell membrane
Between 5 and 10 nm
What is the glycocalyx
The glycocalyx is outside the membrane of cells and is formed by carbohydrate chains attached to either lipids (glycolipids) or proteins (glycoprotein) in the membrane.
Describe the different compositions of cell membranes in neurones, white blood cells and root hair cells
In neurone, the protein channels and carriers in the plasma membrane covering the long axon allow entry and exit of ions to bring about the conduction of electrical impulses along their length. As well as this they have a myelin sheath formed by flattened cells wrapped around them several times, giving several layers of cell membrane. This is about 20 percent proteins and 76 percent lipids, making the axon incredibly insulated.
The plasma membrane of white blood cells contain special protein receptors that enable them to recognise the antigens on foreign cells, usually from invading pathogens but also from tissue or organ transplants.
Root hair cells in plants have many carrier proteins to actively transport nitrate ions from the soil and into cells
The inner membranes of mitochondria are 76 % protein and 24 % lipid. This is because their inner membrane contain many electron carriers that are made of protein, and hydrogen ion channels associated with ATP synthase enzymes.
What is simple diffusion and describe its process
All molecules have kinetic energy and can move freely and randomly within gas or liquid media. This will happen even if the medium is not mixed by stirring or shaking. If there is a higher concentration of a certain type of molecule in an area, then the molecules will bump into eachother as they randomly move, and eventually they will spread further from each-other. More will move to an area of low concentration, until eventually they become evenly dispersed. They reach equilibrium as there is no net movement. Some molecules which are small and non polar can pass through membranes by this process of simple diffusion. A-swell as this, fat-soluble molecules such as steroid hormones, even if they are larger, can diffuse through as they dissolve in the lipid bilayer.
How do water molecules diffuse across plasma membranes
Water molecules are a special case. Since they are polar and insoluble in the lipid bi layer it would seem impenetrable. However water, is present in such great concentrations that significant direct diffusion does happen. In membranes where a very high rate of water molecules are required there may be specific water channel proteins known as aquaporins. These allow water across the membranes without moving through lipid environment.
How is concentration maintained and give two examples
Many molecules entering cells then pass into organelles are used for metabolic reactions: this maintains a concentration gradient and keeps more molecules entering cells. For example. Oxygen diffusing into the cytoplasm of respiring cells then diffuses into mitochondria and is used for aerobic respiration.
As well as this carbon dioxide diffusing into palisade mesophyll cells of plants will then diffuse into chloroplasts and can be used for photosynthesis.
What factors effect the rate of simple diffusion
Simple diffusion relies only on the molecules’ own kinetic energy. And so factors that alter thus kinetic energy will effect this rate of diffusion. For example temperature. As temp increases, molecules have more kinetic energy so their rate if diffusion will increase. Conversely, if they loose heat rate of diffusion slows down.
-diffusion distance, the thicker the membrane across which molecules have to diffuse, the slower the diffusion rate
-surface area, more diffusion can take place across a larger surface area. Cells specialised for absorbsion have extensions to increase their surface area. For example microvilli.
-size of diffusion molecule- smaller ions or molecules diffuse more rapidly than larger molecules
-concentration gradient- the steeper this gradient the faster the diffusion to the side with fewer molecules.
What is facilitated diffusion
Facilitated diffusion is a type of diffusion in which the molecules move from the region of higher concentration to the region of lower concentration assisted by a carrier. It occurs when small molecules have polarity, such as ions with an electrical charge so they cannot pass through the lipid bilayer due to the hydrophilic and hydrophobic tails and heads.
What protein support diffusion do neurone have
Neurone plasma membranes have many channels specific to either sodium or potassium ions. The diffusion of these ions into and out of the neuron axon is crucial to the conduction of nerve impulses. At synapses, there are also calcium ion channels.
What protein support diffusion do epithelial cells have
The plasma membranes of epithelial cels that line your airways have chloride ion channels, and these play a crutial role in regulating the composition of mucus to trap particles and pathogens.
What is the function of the transport protein: channel protein
They create hydrophilic channels to transport polar molecules and ions that cannot pass through the hydrophobic tails of the phospholipid bilayer. It is a type of facillitated diffusion and it is never an active process.
What is the function of the transport protein: carrier proteins
Specific to particular ions or molecules that are too large to fit through phospholipids. This is a type of facilitated diffusion that is active, as it uses ATP to help with it conformational change.
What is the term for when a molecule has both hydrophobic and hydrophilic areas
Amphipathic
What is the function of glycolipids
Glycolipids are carbohydrates attached to the hydrophilic phosphate group head. It helps in cell signalling and recognition.
Define the term osmosis
Osmosis is the net movement of water molecules from an area of high water potential to low water potential across a partially permuable membrane.
What is water potential
Water potential is the measurement of the tendency of water molecules to diffuse from one region to another