Biological Molecules Flashcards

(30 cards)

1
Q

Are all molecules carbon based?

A

Biological molecules are carbon based except for some inorganic molecules

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2
Q

What roles do small molecules often play ?

A

As building blocks for macromolecules and as some other specific function in their own right

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3
Q

What is the Composition of a cell?

A

Water 70%
Inorganic ions 1%
Small organic molecules 3%
Macromolecules 26%

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4
Q

What is the general formula for sugars ?

A

(CH2O)n

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5
Q

What are some functions of carbohydrates?

A

Energy storage , fuel, metabolite and structural element

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6
Q

What are the two types of monosaccharides?

A

Ketone based or aldehyde based

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7
Q

What does it mean for a carbon atom to have a chiral centre?

A

The molecules can make mirror images of each other,can never superimpose so therefore are enantiomers

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8
Q

State the location of the ketone/aldehyde group in the D configuration of glucose

A

The aldehyde/ketone group will be most distant from the asymmetric c-atom

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9
Q

Condensation reaction

A

One molecule of H2O is released for every bond formed in a reaction

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10
Q

Why can we not break down cellulose?

A

Cellulose contains 1-4 beta glycosidic bonds which we cannot break down

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11
Q

How does glycogens structure help its function?

A

Glycogen is branched and therefore able to form 1-6 bonds aswell as 1-4 ,enabling more molecules of sugar to be packed together in one space.

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12
Q

What is an oligosaccharide ?give an example

A

Polysaccharide with different types of monosaccharides

Eg: blood group

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13
Q

What triggers the breakdown of glycogen and what does it break down into?

A

Tyrosine triggers the breakdown into adrenaline

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14
Q

How is histidine converted into histamine ?

A

Histidine is converted into histamine through the loss of CO2 in a vasodilator

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15
Q

What makes up a nucleotide ?

A

Sugar,phosphate and base

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16
Q

Why is sugar-phosphate binding important ?

A

Creates chains which are needed when DNA forms a double helix .
In a DNA helix,chains are going anti-parallel from 5’ end to the 3’ end

17
Q

Why is Adenosine 3’,5’-cyclic monophosphate(cAMP) important?

A

It is essential for blood pressure regulation

18
Q

What is Adenosine 5’ -monophosphate(AMP) involved in?

A

RNA synthesis

19
Q

What produces more ATP ,fats or glucose?

A

Fats produce significantly more ATP than glucose on its own

20
Q

Where do you find saturated fats(unhealthy) ?

A

Found predominantly in animal fats that we consume within our diets

21
Q

Why are saturated fats considered healthy fats?

A

A reactive metabolite would react with the fatty acid , breaking the double bond . Providing an energy source from that , metabolite and can then be reabsorbed by the fatty acid instead of going elsewhere

22
Q

Describe a triglyceride

A

One glycerol reacting with 3 fatty acids joined by an ester bond .releasing one molecule of water per bond

23
Q

Describe a phospholipid

A

One glycerol , two fatty acid chains and one phosphate group and one head group

24
Q

Give some functions of lipids

A

Phospholipid bilayer
Liposome
Micelle(fats transported throughout the body )
Bilayer sheet

25
What is cholesterol?what enables it to intercalated into the membrane?
A steroid | Different components of its structure
26
What parts of cholesterol do the phospholipids react with?
Oh group reacts with polar head and steroid scaffold reacts with fatty acids
27
Why is cholesterols role in the membrane so important ?
Cholesterol decreases fluidity and increases flexibility of the membrane . It reduces permeability for soluble molecules and helps stabilise the membrane with transmembrane proteins which help increase rigidity
28
Diabetes (insulin dependant)
Absence of a protein hormone (insulin)leads to failure to regulate blood glucose
29
Sickle cell disease
One amino acid change (glutamic acid to a valine) in a gloving chain causes haemoglobin to aggregate into polymers -changes red blood cell nick cave disc to moon shape
30
Cystic fibrosis
Absence of a membrane protein that transports chloride leads to altered properties of secretions