Biological Psychology Flashcards
what are neurotransmitters?
chemicals manufactured within neurons
released in response to the arrival of an action potential
have an observable effect on the postsynaptic cell - excitatory postsynaptic potential (EPSP) or inhibitory postsynaptic potential (IPSP)
agonists vs. antagonists
agonists increase activity at the synapse
antagonists decrease activity at the synapse
amino acid neurotransmitters
GABA (gamma amino butyric acid) and glutamate
GABA
gamma amino butyric acid
widely distributed throughout the brain and spinal cord
major inhibitory neurotransmitter of the CNS
example agonist: benzodiazepines (Valium)
glutamate
major excitatory neurotransmitter of the CNS
example antagonist: alcohol (produces sedative effects)
catecholamines
dopamine
epinephrine
norepinephrine
dopamine
can be excitatory or inhibitory
influences movement, learning, attention, and emotion
too much dopamine
schizophrenia
too little dopamine
Parkinson’s disease
norepinephrine
can be excitatory or inhibitory
found in CNS and PNS
alertness, arousal, and mood regulation
too much norepinephrine
sleeplessness, anxiety, mania
too little norepinephrine
depression
tricyclic antidepressants block reuptake of norepinephrine and agonists for norepinephrine
serotonin
indolamine
can be excitatory or inhibitory
influences mood, eating, sleeping, arousal, pain regulation
5-HT
too much serotonin
hallucinations
agonists include LSD and MDMA
too little serotonin
depression and anxiety
acetylcholine
excitatory
found in CNS and PNS
responsible for all muscular movements
too much acetylcholine
muscle cramps and spasms
too little acetylcholine
muscles cannot contract, paralysis
curare is an ACh antagonist and used as a paralytic during surgery