Biological Therapy for Schizophrenia Flashcards
(12 cards)
1
Q
what are the two types of antipsychotics?
A
- atypical
- typical
2
Q
what is the difference between typical and atypical antipsychotics?
A
- atypical has fewer side effects than typical
- atypical binds to a range of receptors and typical only binds to dopamine receptors
- atypical works on positive and negative symptoms
- typical 1950s and atypical 1970s
3
Q
what is an example of a typical antipsychotic?
A
- dopamine antagonists
–> e.g. chlorpromazine
4
Q
what are dopamine antagonists?
A
- block dopamine receptors in the synapses of the brain, reducing action of dopamine
- reduces the positive symptoms like hallucinations
5
Q
what are examples of atypical antipsychotics?
A
- risperidone
- clozapine
6
Q
how does clozapine work?
A
- atypical antipsychotic
- binds to dopamine, serotonin and glutamate receptors
- this actions improves mood and reduced depression and anxiety in patients, it can also improve cognitive functioning
- improves positive and negative symptoms
7
Q
why may clozapine been used?
A
- it has mood enhancing effects
8
Q
what is a side effect of clozapine?
A
agranulocytosis
9
Q
what is risperidone?
A
- atypical antipsychotic
- binds to dopamine and serotonin receptors
- binds more strongly to dopamine receptors than clozapine = effective in much smaller doses
10
Q
what may chlorpromazine be used for?
A
- effective as a sedative
- can act as a sedative due to its effects on histamine receptors
- chlorpromazine is used to calm individuals
11
Q
what are strengths of antipsychotics?
A
+ evidence to support the effectiveness
12
Q
what are limitations of antipsychotics?
A
- likelihood of side effects
- ethical issues
