Biological Treatments For Schizophrenia Flashcards
antipsychotics KW
drugs used to reduce the intensity of symptoms of psychotic conditions such as schizophrenia
typical antipsychotics KW
the first generation of antipsychotic drugs that reduce the effect of dopamine by blocking D2 receptors so dopamine can’t be activated, for example chlorpromazine
atypical antipsychotics KW
drugs developed after typical antipsychotics that reduces the effect of dopamine, serotonin and glutamate by blocking their receptor sites so they can’t be activated, for example clozapine and Risperidone
drug therapies
- can be taken as tablets,injectiona or syrup
- injections usually available for those who are at risk of forgetting
- can be required short ot long term
- some make symptoms disappear in some patients and others not
- split into typical and atypical antipsychotics
how is chlorpromazine taken and how does it work?
- tablets, injections or syrup
- typical dosage is 400-800mg
- reduces action of dopamine by blocking D2 receptor sites in synapse
side effects of chlorpromazine
- calms people to stop people who are highly anxious
- sedative
- itchy skin
- weight gain
- dyskinesia ( involuntary motor movements) long term effect
what symptoms doea chlorpromazine reduce?
- hallucinations
why were atypical drugs introduced?
to reduce side effects of typical antipsychotics
how is clozapine taken?
- tablet as it’s too dangerous is other forms
- typical dosage is 300-400mg
how is Risperidone taken?
- tablet , injection or syrup
- typical dosage is 4-8mg so can be taken in smaller dosages
how does clozapine and Risperidone work?
stops dopamine, serotonin and glutamate being activated by blocking their receptors
side effects of clozapine and Risperidone
- mood enhancing
- agranulocytosis ( blood condition caused by clozapine)
- Risperidone has fewer symptoms
what symptoms do atypical drugs reduce?
- depression and anxiety which improves cognitive function
- helps avolition
- mood enhancing to stop suicidal thoughts
