Biologicos Flashcards

(50 cards)

1
Q

Alemtuzumab

A

AntiCD52

Tx renal
LLC

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2
Q

Basiliximab

A

Anti IL2

Tx renal

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3
Q

Rituximab

A

AntiCD20

GMN mb
LLC

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4
Q

Ofatumumab

A

AntiCD20

LLC

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5
Q

Eculizumab

A

AntiC5

SHU atípico
HPN

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6
Q

Obinutuzumab

A

AntiCD20

LLC

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7
Q

Imatinib
Nilotinib
Dasatinib

A

Inhb TK p120

LMC
GIST

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8
Q

Ruxolitinib

A

Inhb TK

LLC 17p o TP53
Recaída l. Manto
Macroglobulinemia Waldestrom

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9
Q

Idelasib

A

Inhb fosfoinositol 3 quinasa

LLC 17p o TP53
Recaída l. Folicular

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10
Q

Veneteclax

A

Inhb Bcl2

LLC17p

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11
Q

Temsirolimus

A

Inhb mTor

Recaídas l. Manto

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12
Q

Brentuximab bedotin

A

AntiCD30

Recaídas LH tras TPH o 2 líneas QT

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13
Q

Bortezomib

A

Inhb proteosoma

MM (+melfalan y prednisone)

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14
Q

Talidomida/lenalidomida

A

Antiangiogenico

MM (+melfalan/prednisone)

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15
Q

Idarucizumab

A

Antídoto Rivaroxaban

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16
Q

Sorafenib

A

Inhb VEGF

CHC estadio C
Ca. Papilar tiroides M+ refractario a radioyodo
Adenoca renal mtx

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17
Q

Regorafenib

A

Inhb multikinasa

CHC estadio C tras Sorafenib
CCR M+
GIST M+ o irresecable refractario a Imitanib y sunitinib

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18
Q

Trastuzumab

A

AntiHER2

Andenoca gastrico Her2+

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19
Q

Infliximab

A

AntiTNFa

EII corticorrefractario, perianal compleja, fistulizante, extraintestinal grave, mantenimiento tras remisión o fracaso de inmunomoduladores.

AR

Psoriasis

Espondiloartropatia anquilopoyetica

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20
Q

Adalimumab

A

AntiTNFa

EII corticorrefractario, perianal compleja, fistulizante, extraintestinal grave, mantenimiento tras remisión o fracaso de inmunomoduladores.

AR

Psoriasis

Espondiloartropatia anquilopoyetica

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21
Q

Golimumab

A

AntiTNFa

EII corticorrefractario, perianal compleja, fistulizante, extraintestinal grave, mantenimiento tras remisión o fracaso de inmunomoduladores.

AR

Espondiloartropatia anquilopoyetica

22
Q

Vedolizumab

A

Anti integrina a4b7

EII corticorrefractario, mantenimiento tras remisión inducida por biológico, mantenimiento con fracaso de terapia convencional y antiTNFs

23
Q

Cetuximab

Panituximab

A

AntiERGF

CCR N/M+

24
Q

Palivizumab

A

AntiVSR

Bronquilotis profilaxis: menos 2a enf pulmonar crónica
RNPT menos 28s x12m
RNPT 29-32s x 6m

25
Ivacaftor/lunacaftor
FQ F508
26
Oseltamovir
Inhb selectivo neuraminidasa gripe
27
Evolocumab
Anti PCSK9 Hipercolesterolemia familiar Muy alto rcv
28
Sunitinib
Inhb TK Carcinoide Ca. Papilar tiroides M+ refractario a radioyodo Adenoca renal mtx
29
Vandenatib
Inhb TK Ca. Medular tiroides M+ progresivo
30
Vismodegib
Inhb hedgehog Ca basocc mtx o localx avanzado no operable
31
Vemurafenib
Inhb mut V600 Braf Melanoma mtx y/o irresecable
32
Dabrafenib
Inhb BRAF Melanoma mtx y/o irresecable
33
Trametinib
Inhb MEK Melanoma mtx y/o irresecable (+dabrafenib)
34
Ipilimumab
Ac antiCTLA4 2a línea melanoma mtx y/o irresecable
35
Nivolumab | Pembrolizumab
Inhb PD1 melanoma mtx y/o irresecable
36
Ranibizumab Aflibercept Bevacizumab
AntiVEFG DMAE húmeda Adenoca renal mtx
37
Muromomab
AntiCD3 Rechazo renal y cardíaco
38
Efalizumab
AntiCD11a (LFA1) Psoriasis
39
Tofacitinib | Bariticinib
Anti JAK AR
40
Cetolizumab
AntiTNF AR
41
Etarnecept
AntiTNF AR Psoriasis Espondiloartropatia anquilopoyetica
42
Ustekinumab
Anti IL12 y 23 Psoriasis
43
Secukinumab
Anti IL17 Psoriasis Espondiloartropatia anquilopoyetica
44
Ixekinumab
AntiIL17 Psoriasis
45
Abatacept
Anti CTLA4 AR
46
Tocilizumab
Anti IL6 Arteritis Tempora Takayasu
47
Belimumab
Inhb prot estimuladora linfosB LES refractarios (NO en riñón o snc)
48
Denosumab
Unión a RANKL (inhb osteoclasto) Osteoporosis mujeres riesgo alto
49
Pasopanib
Inhb TK Adenoca renal mtx
50
Axitinib
Inhb TK Adenoca renal mtx