Bipolar Disorder Flashcards

1
Q

Bipolar I

A

at least one episode of mania alternating with major depression

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2
Q

Bipolar II

A

one or more episodes of hypomania alternating with major depression

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3
Q

mania

A

severe impairment lasting 1 week that usually requires hospitalization to prevent harm with 3+ symptoms

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4
Q

hypomania

A

change in functioning lasting at least 4 days

reality testing is not impaired and hospitalization is not usually required

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5
Q

rapid cycling

A

2+ episodes of alternating mania/depression in a 12 month period

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6
Q

mixed features

A

depressive symptoms occur during manic episode

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7
Q

mania symptoms X7

A
inflated self/esteem
decreased need for sleep
more talkative
flight of ideas
distractibility
increase in goal directed activity
excessive involvement in activities with high potential for consequences
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8
Q

unipolar depression clinical picture

A

may be present with manic symptoms but they do not meet criteria for diagnostic

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9
Q

bipolar depression medication

A

antidepressants must be used in conjunction with mood stabilizers

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10
Q

unipolar depression s/s X5

A
  • affects more women than men
  • appears later in life
  • loss of appetite
  • insomnia
  • lesser risk of drug abuse/suicide
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11
Q

bipolar depression s/s X5

A
  • affects women and men equally
  • onset younger age
  • alt binge eating/anorexia
  • hypersomnia and difficulty waking
  • greater risk of drug abuse/unipolar
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12
Q

comorbidities with bipolar disorder

A

-substance use disorders
-anxiety disorders
-borderline personality
ADHD

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13
Q

genetics and biopolar

A

strong genetic factor

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14
Q

neurotransmitters and bipolar

A

epi and nor epi high in mania and low in depressino

serotonin and dopamine affected too

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15
Q

psychosocial factors of bipolar

A

may be triggered by stress

more prevalent in upper socioeconomic classes

high among writers, artists, highly educated professions

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16
Q

acute phase planning

A

medical stabilization and maintaining safety

potential hospitalization

17
Q

continuation phase planning

A

relapse prevention via:

medication compliance, psycho-education, referrals, support groups

18
Q

maintenance phase planning

A

relapse prevention through coping strategies, psychotherapy, recovery/support groups

19
Q

communication

A

be firm and calm

short and concise statments

clear limit setting

firmly redirect and distract PRN

20
Q

antidepressants and bipolar

A

should not be given alone - must use mood stabilizers

hypomania/mania may result

21
Q

preferred antidepressants with bipolar

A

bupropion, venlafaxine or SSRI’s

22
Q

preferred antipsychotics with bipolar

A

onlanzapine, quetiapine, risperidone, ziprasidone

23
Q

first line treatment bipolar

A

lithium

24
Q

lithium MOA

A

alters excitatory neurotransmitters and neuronal activity

25
Q

lithium maintenance level and onset time

A

0.4-0.1, effects begin in 5-7 days but may take 2-3 weeks for full effect

26
Q

lithium SE X4

A

hand tremor
polyuria
nausea
weight gain

27
Q

long term risks of lithium

A

hypothyroidism
kidney impairment

contraindicated in pregnancy

28
Q

severe lithium toxicity SE X8

A
ataxia
EKG changes
blurred vision
clonic movements
polyuria
seizures
hypotension
pulmonary complications
29
Q

severe lithium toxicity level

A

2.0-2.5

30
Q

lithium pt ed X7

A

monitor blood levels, thyroid, kidney level

maintain salt and fluid intake

s/s of toxicity

do not take diuretcs/OTCs

avoid pregnancy

take with meals

do not stop abruptly

31
Q

mood stabilizers MOA

A

depresses CNS by increasing GABA

32
Q

mood stabilizers X8

A
divalproex
valproate
valproic acid
carbamazepine
lamotrigine
gabapentin
topiramate
oxcarbazepine