Bipolar Drugs Flashcards
(5 cards)
1
Q
Drug therapy for Bipolar Disorder
A
- mood stabilizers (Lithium, antiepileptic drugs)
- Antipsychotics (during manic episodes)
- Antidepressants (during depressive episodes)
2
Q
Therapeutic Uses of Lithium
A
- bipolar disorder
- bulimia
- schizophrenia
- glucocortocoid induced psychosis
3
Q
Mechanism of Action of Lithium
A
- altered distribution of some ions
- altered synthesis and release of NE, serotonin, and dopamine
- Mediates intracellular responses to neurotransmitters
- shown to facilitate regeneration of damaged optic nerves
- can increase total gray matter in regions known to atrophy in Bipolar disorder
4
Q
Adverse Effects of Lithium
A
- excessive lithium levels
- gastrointestinal issues
- tremors
- polyuria
- renal toxicity
- goiter and hypothyroidism
- teratogenesis
5
Q
Drug interaction of Lithium
A
- diuretics can cause toxicity
- NSAIDs
- Anticholinergic drugs
