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Y1 Pharmacology > Bisphosphonates - Week 13 PBL > Flashcards

Bisphosphonates - Week 13 PBL Flashcards

1
Q

How do bisphosphonates work?

A

Inhibit osteoclast activity

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2
Q

Key side effects of bisphosphonates?

A

Reflux and oesophageal erosions
Atypical fractures
Osteonecrosis of jaw
Osteonecrosis of external auditory canal

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3
Q

How must bisphosphonates be taken to reduce side effects?

A

Sat upright
Empty stomach
Wait 30 mins before moving or eating

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4
Q

Examples of bisphosphonates?

A

Alendronate 70mg oral weekly
Risedronate 35mg oral weekly
Zolendronic acid 5mg yearly IV

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Y1 Pharmacology (7 decks)

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