Bladder Flashcards
1
Q
Describe T staging
A
T1 subepithelial T2 invades muscle T2a invades inner half T2b invades outer half T3. Invades perivesicle tissue T3a microscopically T3b macroscopically T4a invades prostate/SV/uterus/vagina T4b invades pelvic or abdominal wall
2
Q
Describe N staging
A
N1 single met in true pelvis (hypo gastric, obturator,Ext iliac or presacral)
N2 met in multiple regional LN in true pelvis
N3 mets in common iliac nodes
3
Q
What neoadjuvant chemotherapy is offered for MIBC?
A
Cisplatin 70mg/m2 D1 and gemcitabine 1000mg/m2 D1&8 q21d
4
Q
What radical chemoradiotherapy is offered?
A
Gemcitabine 100mg/m2 weekly with XRT 52.5Gy/20# over 4/52
Or
55Gy/20# with carbogen 15L/min for 5min before and during and nicotinamide 60mg/kg 2h before