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Systems 2nd Year Renal > Bladder Cancer > Flashcards

Bladder Cancer Flashcards

1
Q

Most common tumour type in Bladder Cancer

A

Transitional Cell Carcinoma

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2
Q

Where schistosomiasis is endemic what cancer histology is common tumour type in bladder

A

squamous cell carcinoma

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3
Q

Risk Factors for Bladder Cancer Transitional Cell Carcinoma

A

Smoking
Aromatic Amines
Non Hereditary Genetic Abnormalities

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4
Q

Which non hereditary genetic abnormalities are associated with Transitional Cell Carcinoma of Bladder Cancer

A

P53 and Rb

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5
Q

Risk Factors for Squamous Cell Carcinoma in Bladder Cancer

A

Schistosomiasis
Chronic Cysitis
Cyclophosphamide Therapy
Pelvic Radiotherapy

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6
Q

Schistosomiasis is related to which bacteria when for bladder cancer

A

S Haemobium

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7
Q

Presenting Features of Bladder Cancer

A

Painless Visible Haematuria
Recurrent UTI
Storage Bladder Symptoms eg Dysuria, Frequency, Nocturia, Bladder Pain

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8
Q

Frank Haematuria

A

reported by patient

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9
Q

Investigations of Haematuria

A 
Urine Culture
CT Urogram
Ultrasound
Urine Cytology
Cystourethroscopy
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10
Q

Investigations of Frank Haematuria

A

> 50 = High Risk Malignancy
Flexible Cystourethroscopy within 2 Weeks
IVU and USS

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11
Q

Investigations of Haematuria on Dipstick or Microscopic?

A

Risk of Malignancy Low
Flexible Cystourethroscopy within 4-6 Weeks
USS

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12
Q

Diagnosis of Bladder Cancer

A

Cystocopy and Endoscopic Resection

EUA to assess bladder

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13
Q

Treatment for Bladder Cancer

A

Endoscopic or Radical

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14
Q

G1 Bladder Cancer

A

Well Diff

Non Invasive

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15
Q

G2 Bladder Cancer

A

Mod Diff

Non Invasive

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16
Q

G3 Bladder Cancer

A

Poorly Diff

Invasive

17
Q

Carcinoma in Situ in Bladder Cancer is

A

very aggressive but doesn’t invade muscles

18
Q

How to Treat Bladder Cancer Low Grade Non Muscle Invasive

A

Endoscopic Resection

Single Intravesical Chemo (Mitomycin C within 24 Hours)

19
Q

How to Treat Bladder Cancer High Grade Non Muscle Invasive or CIS

A

Very Aggressive

Radical Surgery

20
Q

How to Treat Muscle invasive Bladder Cancer (T2 or T3)

A

Neoadjuvant Chemo for Local
Radical Radiotherapy
Radical Cystoprostectomy (Men) or Anterior Pelvic Extenteration with Uretherectomy (Women)

Systems 2nd Year Renal (30 decks)

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