Block 5 . . . .

Question 1

What viral associated polymerase is associated with negative RNA virus?

Answer 1

RNA-dependent RNA polymerase

Question 2

Negative RNA are?

Answer 2

Helical

Question 3

Positive RNA is

Answer 3

Icosahedral

Corona is helical

Question 4

Negative RNA enveloped

Answer 4

“BARF-PO”

Bunya
Arena
Rhabdo
Filo
Paramyx 
Orthomyxo

Question 5

Positive RNA enveloped

Answer 5

Think of being positive as wearing a toga , eating flavor, and drinking corona.

Toga
Flavi
COrona

Question 6

Positive Naked RNA

Answer 6

Pico

Cali

Question 7

dsRNA

Answer 7

Reo “Rotavirus”

Question 8

Features of naked viruses

Answer 8

Tough
contains viral attachment proteins
survives on fomites
Survives the GI tract

Question 9

Enveloped viruses must be maintained in

Answer 9

water

Question 10

Use VP1 canyon and ICAM

Answer 10

Rhinovirus and enterovirus

Question 11

Prevents binding of gp120 in HIV?

Answer 11

Maraviroc

Question 12

Prevents VP1 from binding to ICAM

Answer 12

Pleconaril

Question 13

Used to treat herpes

Answer 13

Acyclovir

Question 14

Used to treat CMV

Answer 14

Gancyclovir

Question 15

The Valcyclovirs are

Answer 15

prodrugs

Question 16

Interferes with capping and elongation of mRNA.

Answer 16

Ribavirin

Question 17

Delayed chain terminator

Answer 17

Remdesivir

Question 18

Treats Hep B

Answer 18

Entecavir

Question 19

Competitiviely inhibits DNA polymerase. Broad activity against DNA viruses.

Answer 19

Cidovir

Question 20

HBV reverse transcriptase

Answer 20

Telbivudine

Question 21

HIV reverse transcriptase

Answer 21

Zidovudine

Question 22

HIV and HBV reverse transcriptase

Answer 22

Adefovir and Tenovir (adenosine)

Lamivudine (cytosine)

Question 23

HIV chain terminators

Answer 23

“DAZE”

Didanosine
Abacavir
Zidovudine
Emtricitabine

Question 24

Antiheroes drug that interferes with pyrophosphate binding site

Answer 24

Foscarnet

Question 25

What are integrase inhibitors?

Answer 25

Keeps DNA from being integrated into host cell (retroviruses)

Question 26

Assembly takes place in cytoplasm for?

Answer 26

RNA viruses

Question 27

NA inhibitors

Answer 27

osletamivir zanamivir peramivir

Question 28

Blocks cap snatching

Answer 28

Baloxavir

Question 29

Non segmented RNA

Answer 29

Filo, Rhabdo, Paramyxo

Question 30

Segmented RNA

Answer 30

Orthomyxo Arenaviruses Bunyaviruses

Question 31

Cytoplasmic replication

Answer 31

``` Filo Arena Bunya Paramyxo Rhabdo ```

Question 32

Nuclear replication

Answer 32

Borna and Orthomyxo

Question 33

Arbo involves | Allen Diles, Paul Bunyan love flavorful food They eat it under the arbor

Answer 33

Flavi Toga Bunya

Question 34

HBsAg

Answer 34

Current

Question 35

Current

Answer 35

HBsAG

Question 36

Recovered or immune

Answer 36

HBsAb

Question 37

HBsAB

Answer 37

recovered or immune

Question 38

HBcAb

Answer 38

Had or Had (IgM or IgG)

Question 39

Had or had IgM or IgG

Answer 39

HBcAB