Block A Lecture 2 (antibody structure and diversity)

Question 1

What are the 3 phases of the immune response to a pathogen

Answer 1

recognition
reaction
resolution

Question 2

what are the 2 types of immune response

Answer 2

innate and adaptive
(cell mediated and antibody mediated)

Question 3

what type of protein are antibodies?

Answer 3

glycoproteins

Question 4

what produces antibodies

Answer 4

B lymphocytes

Question 5

what do antibodies recognise?

Answer 5

proteins
carbs
nucleic acids
glycolipids
small inorganic molecules

Question 6

what responses can antibodies mediate?

Answer 6

interact with complement (cell lysis/attach innate cell)
interact with phagocytic cells (via Fc portion)
can have a neutralising effect (e.g block viral entry to cells)

Question 7

what are the 5 classes of antibodies?

Answer 7

IgG (has 4 sub classes)
IgD
IgE
IgA
IgM

Question 8

what do antibodies consist of?

Answer 8

4 polypeptide chains
2 heavy and 2 light
heavy determines isotype