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PHARMACOLOGIE > Blonde de Simon > Flashcards

Blonde de Simon Flashcards

1
Q

Doxorubicine

A

Substrat/inhibe GP

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2
Q

Vincristine

A

Substrat/inhibe GP

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3
Q

Vinblastine

A

Substrat/inhibe GP

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4
Q

Digoxine

A

Substrat/inhibe GP
CV

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5
Q

Diltiazem

A

Substrat/inhibe GP
CV

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6
Q

Verapamil

A

Substrat/inhibe GP
CV

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7
Q

Hormone stéroïdienne

A

Substrat/inhibe GP

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8
Q

Cyclosporine

A

Substrat/inhibe GP
réduit seuil épileptiforme
= immunosuppresseur

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9
Q

Tacrolimus

A

Substrat/inhibe GP
= immunosuppresseur

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10
Q

Erythromicine

A

Substrat/inhibe GP
= atb

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11
Q

Tetracycline

A

Substrat/inhibe GP
atb

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12
Q

Ketoconazole

A

Substrat/inhibe GP
= anti-fongi

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13
Q

Lopéramide

A

Substrat/inhibe GP
= opiode

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14
Q

Butorphanol

A

Substrat/inhibe GP

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15
Q

Morphine

A

Substrat/inhibe GP

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16
Q

Ivermectin

A

Substrat/inhibe GP
= anti-parasite

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17
Q

Odansétron

A

Substrat/inhibe GP
= anti-émétique

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18
Q

Dompéridone

A

Substrat/inhibe GP

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19
Q

Moxidectine (imidaclopride)

A

Substrat/inhibe GP
= antiparasitaire

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20
Q

ACP

A

Substrat/inhibe GP
+/-Réduit seuil épileptiforme

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21
Q

Milbémycine

A

Substrat/inhibe GP
= antiparasitaire

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22
Q

jus pamplemousse, raisin, herbe chinoise, millepertuis

A

substrat/inhibe GP

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23
Q

Sulfamides

A

Pénètre BHE
= atb

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24
Q

Chloramphénicol

A

Pénètre BHE
= atb

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25
Q

Métronidazole

A

Pénètre BHE atb
E/S neuro

= atb NITROIMIDAZOLE et antiprotozoaire
anaérobe

Mécanisme: réduit ADN

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26
Q

Enrofloxacine

A

Pénètre BHE
Réduit seuil des crises épileptiformes
= atb

27
Q

Céphalosporine 3e

A

Pénètre BHE
réduit seuil des crises épileptiformes
= atb

28
Q

Doxycycline

A

Substrat/inhibe GP
Pénètre BHE
= atb rickettsies

29
Q

Clindamycine

A

Pénètre BHE
= atb protozoaire
mieux si combiné TMS

30
Q

Fluconazole (triazolé)

A

Pénètre BHE
= anti-fongi

31
Q

Voriconazole

A

Pénètre BHE
= anti-fongi

32
Q

Itraconazole

A

Pénètre BHE,substrat GPP
= anti-fongi

33
Q

Lomustine

A

Pénètre BHE
= anti-cancer

34
Q

Carmustine

A

Pénètre BHE
= anti-cancer

35
Q

Cytarabine A

A

Pénètre BHE
= anti-cancer

36
Q

Hydroxyurée

A

Pénètre BHE
= anti-cancer

37
Q

Pénicilline

A

réduit seuil crise épileptiforme
(IR)

38
Q

Imipénème

A

réduit seuil crise épileptiforme
= atb

39
Q

ATB à éviter si patient épileptique (4)

A

CÉPHALOSPORINE, ENROFLOXACINE, PÉNICILLINES, IMIPÉNÈME

40
Q

Tramadol

A

réduit seuil épileptiforme

41
Q

Opioïdes

A

réduit seuil épileptiforme

41
Q

Antidépresseur tricyclique

A

réduit seuil épileptiforme

42
Q

Méthylphénidate (Ritalin) ⁄ stimulants

A

réduit seuil épileptiforme

43
Q

Aminoglycoside

A

OTOTOXICITÉ
E/S SN

44
Q

Streptomycine

A

aminoglycoside = vestibulaire

45
Q

Gentamycine

A

aminoglycoside = vestibulaire

46
Q

Furosémide

A

augmente ototoxicité aminoglycoside

47
Q

Néomycine

A

Aminoglycoside = auditif

48
Q

Kanamycine

A

Aminoglycoside = auditif

49
Q

Latobramycine

A

Aminoglycoside = auditif

50
Q

Sulfate d’amikacine

A

Aminoglycoside = auditif

51
Q

Sarolaner (Simparica)

A

isoxazoline

52
Q

Afoxolaner (Nexgard)

A

isoxazoline

53
Q

Fluralaner (Bravecto)

A

isoxazoline

54
Q

Lotilaner (Credelio)

A

isoxazoline

55
Q

isoxazoline

A

affecte SN (possible épilepsie)

56
Q

Benzodiazépam (diazépam, midazolam)

A

anti-convulsivant

57
Q

Phénobarbital

A

anti-convulsivant

58
Q

Levetiracetan

A

IV
anti-convulsivant

59
Q

KBr

A

PO
anti-convulsivant

60
Q

Propofol

A

bolus
anti-convulsivant

61
Q

Kétamine

A

bolus
anti-convulsivant

62
Q

Dexmédétomidine

A

bolus
anti-convulsivant

PHARMACOLOGIE (6 decks)

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