Blood 1

Question 0

Synergistically acts (syn==oppose?!) w other growth factors to stimulate megakaryocyte

Answer 0

Opeevelkin

Question 1

3 megakaryocyre growth factors

Answer 1

ORE
Oprevelkin
Romiplostim
Eltrombopag

Question 2

Peptibody; used for chronic idio thrombocytopenia

Answer 2

Romiplostim

Question 3

Oral receptor agonist for severe idio thrombocytopenia

Answer 3

Eltrombopag

Question 4

Presebt ib early progrnitor cells but not in late

Answer 4

Cd34

Question 5

More specific myeloid gf; doc for pbsc mobilization

Answer 5

Filgrastim

Question 6

Adverse effect of filgrastim

Answer 6

Splenomegaly w bone pain

Question 7

Less specific; less effective! Than G Csf; multipotential hematopoietic; gm csf

Answer 7

SarGramostim

Question 8

Adverse effect of sargeamostim

Answer 8

Capillary leak syndrome

Question 9

For febrile neutropenia

Answer 9

Pegfilgrastim

Question 10

First hematopoietic growth factor isolated

Answer 10

Erythropoietin

Question 11

High bone marrow disorders and low anemia of chronic renal failure

Answer 11

Endogenous EPO

Question 12

Normal stores of folate

Answer 12

5-20 mg

Question 13

Folate completely absorbed in?

Answer 13

Proximal jejunum

Question 14

Required for vit b12 dependent reaction generating met from homocysteine

Answer 14

N methyl thf

Question 15

Folate supplementation on cancer chemotherapy

Answer 15

Leucovorin

Question 16

Popular sequelae of folic acid deficiency

Answer 16

Spina bifida

Meningocele

Question 17

Normal daily requirement if vit b12

Answer 17

1-5microgram

Question 18

Megaloblastic with neurologic synptoms?

Answer 18

B12 deficiency

Question 19

Diagnosis of b12

Answer 19

Schilling test (urinary excretion of radioactive b12)

Question 20

B12 form that is highly protein bound

Answer 20

Hydroxycobala

Question 21

Thearapy dose of b12

Answer 21

100-1000mcg/day every other day for 2 wks

Not complexed w intrinsic factor

Question 22

Normally absorbed Fe in the duode and p jejunum

Answer 22

0.5-1 mg

Question 23

Inhibits intestinal cell iron release

Answer 23

Hapcidin

Question 24

Form of treatment for ida in px with chronic kidney ds

Answer 24

Parenteral

Question 25

Treatment for acute iron toxicity ( 10tab)

Answer 25

De-fero-xamine

Question 26

Dose of iron given daily?

Answer 26

200-400mg (only 50-100 absorbed)

Question 27

Take with iron?

Never take with iron?

Answer 27

C

Antacids and al salts

Question 28

Parenteral iron less likely to cause hypersensitivity

Answer 28

Na ferric gluconate

Iron sucrose