blood Flashcards
(29 cards)
what does blood transport (7 things)
gases, waste products of metabolism, hormones, nutrients, plasma proteins, blood cells
what does blood regulate?
body fluid electrolytes
how does the blood protect the body?
removes toxins, regulates blood clotting
what is the ph of blood
7.35 - 7.45 (slightly alkaline)
what are the three components of blood (and their proportions)
red blood cells (44%), white blood cells and platelets (1%), plasma (55%)
science name for red blood cells
erythrocytes
science name for white blood cells
leukocytes
science name for platelets
thromocytes
what types of RBCs are found in iron deficiency anaemia?
microcytic
what types of RBCs are found in folate deficiency anaemia?
macrocytic
what is the structure of haemoglobin
4 protein chains; 2 alpha, 2 beta. contains 2 iron containing ham groups
what Is the name of the molecule when oxygen is bound to haemoglobin
oxyhaemoglobin
in the lungs, what does the partial pressure of oxygen mean for Hb saturation
nearly 100% saturated with oxygen
which part of Hb is mutated in sickle cell anaemia
the beta chain is mutated
can carbon dioxide bind to Hb
yes
what is haemostasis
the arrest of bleeding from a broken blood vessel
what are platelets
small cell fragments, anuclear
what are the 3 steps of haemostsis
1) vascular spasm
2) formation of platelet plug
3) blood coagulation/clooting
during vascular spasm, what happens to the blood vessels and muscle layer?
blood vessel constrict. Muscle layer surrounding a cut blood vessel immediately constricts slowing blood flow
what do platelets use to to form a platelet plug?
von Willebrand’s factor - a plasma protein secreted by endothelial cells and platelets
what do platelets bind to in order to become sticky
collagen
what does vessel lining normally release to inhibit platelet aggregation
prostacyclin - means platelet plug does not spread to normal tissue
what do clots form on top of and why
platelet plugs, to strengthen, support and reinforce it
fibrinogen is converted to … by enzyme … to form clot
fibrin, thrombin