Blood Flashcards
(49 cards)
What is blood?
Blood is a connective tissue. Blood transports substances throughout the body and maintains a stable internal environment. Blood includes RBC, WBC, platelets, and plasma
Plasma
A mixture of water, amino acids, proteins, carbohydrates, lipids, vitamins, hormones, electrolytes, and cellular wastes. A blood hematocrit is normally 45% of the cells and 55% plasma
Erythrocytes
Red blood cells. Biconcave disks that contain on-third oxygen carrying hemoglobin by volume. They discard their nuclei during development so they can’t reproduce or produce proteins.
Hemoglobin
Chemical that binds with oxygen. ( the protein molecule in red blood cells that carries oxygen from the lungs to the body’s tissues and returns carbon dioxide from the tissues back to the lungs.)
Oxyhemoglobin
When oxygen combines with hemoglobin. It is bright red
Deoxyhemoglobin
Deoxygenated blood. It is darker than regular blood
Blood doping
When you have an increased amount of RBC in your system, so you have a higher oxygen-carrying capacity.
Where does RBC production occur in the embryo and fetus?
In the yolk sac, liver, and spleen
After birth where does RBC production occur?
In the red bone marrow
What is the average life span of a RBC?
120 days
Hematopoietic stem cells
Produce red blood cells. They are in the red bone marrow and are derived from the mesoderm
Erythropoietin
The hormone released from the kidneys and liver in response to the detection of low oxygen levels.
What two things are needed for the reproduction of DNA and hematopoietic tissue?
Vitamins B12 (iron) and folic acid
Anemia
A deficiency in RBC or quantity of hemoglobin results in anemia
Macrophages
In the liver and spleen phagotize damaged RBC
What is the hemoglobin in the decomposed RBC converted into?
Heme and globin
What is heme decomposed into?
Iron, which is stored in biliverdin and bilirubin which are excreted in bile.
Leukocytes
White blood cells. They help defend the body against disease. Formed by hemocytoblasts.
What are the two categories of hormones that stimulate WBC production
Interleukins and colony-stimulating factors (CSF’s)
What are the five type of WBC
(Granulocytes?), neutrophils, eosinphils, and basophils, and the (agranulocytes?) which are monocytes and lymphocytes
Neutrophils
They’re WBC and they are the most common ones found in the body
Eosinophils
They make up only 1-3% of circulating leukocytes. (a white blood cell containing granules that are readily stained by eosin.) Moderate allergic reactions and defend against parasitic infections.
Basophils
Only make up fewer than 1% of leukocytes. They migrate to damaged tissues and release histamine to promote inflammation and heparin to inhibit blood clotting
Monocytes
The largest blood cell. Have variably shaped nuclei and make up 3-9% of circulating leukocytes. (Have the ability to engulf)