Blood Chapter 19 Flashcards
(22 cards)
WHOLE BLOOD
FLUID PLASMA
AND
FORMED ELEMENTS
FUNCTIONS OF BLOOD
Transport
Regulation
Diffusion
Restricting fluid losses at injury site
Defending against Toxins and Pathogens.
Stabilizing Body Temperature.
How does blood works as a transport?
Transport OXYGEN, CARBON DIOXIDE, NUTRIENTS
From my meals, metabolic waste so I can go
Thru excrete process, and HORMONES
DELIVERS ANTIBODIES, PROTEINS.
EXPLAIN HOW BLOOD WORKS AS A REGULATOR
(REGULATION)
Regulates Ph, Ions, and Interstitial fluid
the interstitial fluid is fluid that bathing my cells,
my blood has a connection with that.
I will have exchange with what ever is in the interstitial fluid what ever is on my blood exchange somethings may leave the blood other things may leave interstitial part of my body
How does blood act as a Restricting Fluid Losses?
Enzymes in blood and other substances that response
To breaks in blood vessels wall, initiate process of clotting
Blood acts as a temporary patch prevents further blood loss
HOW DOES BLOOD WORKS AS “DEFENDING AGAINST
TOXINS AND PATHOGENS”
BLOOD IS A DEFENSE MECHANISM
IN BLOOD I HAVE WBC (fight infections )
If WBC is to high my body is trying to fight something
BLOOD STABILIZING BODY TEMPERATURE
BLOOD ABSORBS HEAT GENERATED BY ACTIVE SKELETAL MUSCLES AND
SHIFT IT TO OTHER TISSUES.
Example: Body temp. To high heat will loss across surface of skin Body temp. To low warm blood is sent to the brain and to Other temperature sensitive organs.
PLASMA PROTEINS IN BLOOD
FIBRINOGEN —–HELPS CLOTTING
4% OF THESE PROTEIN IN PLASMA
ALBUMINS ----- OSMOTIC PRESSURE OF PLASMA 60% MOST ABUNDANT OSMOTIC ANOTHER WORD "MAINTAIN BALANCE" GLOBULINS. ----- ANTIBODIES & TRANSPORT GLOBULINS 35%
FORMED ELEMENTS FOUND IN WHOLE BLOOD
PLATELETS
ERYTHROCYTES (RBC)
WHITE BLOOD CELLS, (WBC) or Leukocytes
FYI: WBC (BENLM) : BASOPHILS, EOSINOPHILS, NEUTROPHILS, LYMPHOCYTES, MONOCYTES)
WHOLE BLOOD IS MADE OUT OF FIVE ELEMENTS
- PLASMA PROTEINS. (ALBUMINS, GLOBULINS, FIBRINOGEN)
2. OTHER SOLUTES. ( ORGANIC NUTRIENTS, ELECTROLYTES, ORGANIC WASTE
3. PLATELETS
4. WHITE BLOOD CELLS
5. RED BLOOD CELLS
HEMOPOIESIS
THE PROCESS THAT PRODUCES FORMED ELEMENTS
(RBC, WBC, PLATELETS)
MYELOID AND LYMPHOID STEM CELLS
HEMATOCRIT
OR
PACKED CELL VOLUME
THE PERCENTAGE (%) OF FORMED ELEMENTS IN A SAMPLE OF BLOOD.
WHAT IS THE PERCENTAGE OF HEMATOCRIT
OR PACKED CELL VOLUME
ADULT MALE AND FEMALE
ADULT MALE: 46
MALE HORMONE “ ANDROGENS”
STIMULATE RBC PRODUCTION
ADULT FEMALE 42 ESTROGENS DO NOT.
HYPOXIA
LOW OXYGEN LEVELS on blood
IN MY TISSUES
LEUKOCYTOSIS
INCREASE OF LYMPHOCYTES (WBC)
DUE TO INFECTION
LEUKOPENIA
LOW NUMBER OF WHITE BLOOD CELLS COUNT
WHY IS ERYTHROPOIETIN (EPO)
BENEFICIAL?
is a glycol protein made by the Kidney and liver.
Erythropoietin is release during anemia, oxygen content in the lungs is low due to high altitude disease, and release when blood flow to kidney declined, parts of lungs are damage
Once is on blood stream Travels to the red Bone Marrow and stimulates the stem cells and developing RBC
Two major effects
Speed up maturation of red blood cell
Stimulates cell division rates in erythroblast and in stem cell that produce erythroblast
THREE REASONS WHY HEMOGLOBIN IS IMPORTANT
- MAKE UP 95 PERCENT AND MORE OF PROTEINS IN RBC
2. RESPONSIBLE FOR CELL ABILITY TO TRANSPORT OXYGEN & CO2
3. SINGLE MOLECULE OF HEME PROTEIN HOLD IRON ION
SO IRON CAN INTERACT WITH OXYGEN MOLECULE
WHY IS NITRIC OXIDE IMPORTANT?
Check withLina
A MOLECULE THAT THE BODY PRODUCES
TO COMMUNICATE WITH EACH OTHER
BY TRANSMITTING SIGNALS THROUGHOUT THE BODY.
NITRIC OXIDE IS IMPORTANT: HELP MEMORY, REDUCE INFLAMMATION
REGULATE BLOOD PRESSURE, IMPROVE SLEEP, HELP GASTRIC MOBILITY
Explain the formation and destruction of red blood cells and recycling
Of hemoglobin components. Fig 19-4
RBC is formed in the Bone Marrow as baby they have a nucleus and hemoglobin, as it matures looses it Nucleus RBC is release to blood stream where it leaves for 120 releases Heme this heme goes to Kidney were is release by Urine. RBC prior to enter Macrophages in Spleen heme contains Iron ions changes into Biliverdin exiting the Spleen changes to Bilirubin is bound to Albumin as is release into the blood stream. Moves down to liver were it gets Excreted by the bile. Some of Heme goes into Kidney gets eliminated by Urine
Large Intestine where Bacteria changes Bilirubin to UROBILINS and Stercobilins, it gives feces yellow/brown color urobilins are eliminated in feces. Some Urobilins are absorbed by the blood stream to the Kidney where gets eliminated by Urine, heme on blood stream enters Kidne
HEMOSTASIS
HAIMA = BLOOD STASIS = HALT
THE STOPPAGE OF BLEEDING
LIST THE THREE STAGES OF CLOTTING
A. EXTRINSIC PATHWAY
B. INTRINSIC PATHWAY
C. COMMON PATHWAY