Blood Donation

Question 1

Minimum age for donation.

Answer 1

17 (without parental consent)

*some states 16 (with parental consent)

Question 2

Viral Hepatitis

Answer 2

Permanent Deferral

• personal hx after age 11
• Positive HBsAg, anti-HBc, reactive anti-HCV

12 Months

• contact with viral hepatitis
• Incarcerated >72 hours

Question 3

CJD

Answer 3

Permanent Deferral:

• > 3 months in UK or 5 years total (1980-1996)
• Family Hx
• Bovine Insulin
• Dural Transplant
• Pituitary derived Growth Hormone

Question 4

HIV

Answer 4

Permanent Deferral:

• HIV+
• Homosex in past 12 months

12 months:
- Healthcare worker exposed to blood of HIV+ pt

Question 5

Babesiosis & Chagas

Answer 5

Permanent Deferral

Question 6

Drugs - > 3 years deferral (4)

Answer 6

Permanent Deferral:

• Tegison (etretinate)
• Human Pituitary Growth Hormone
• Bovine Insulin

3 year deferral:
- Soriatane (Acitretin)

Question 7

Drugs - 24 month (3)

Answer 7

• Erivedge (vismodegib)
• Odomzo (sonidegib)
• Aubagio (teriflunomide)

Question 8

Drugs - 12 month (2)

Answer 8

• HepB immunoglobulin (HBIG)

- Experimental drug or vaccine

Question 9

Drugs - 6 month (1)

Answer 9

Dutasteride (avodart)

Question 10

Drugs - 1 month (2)

Answer 10

• Isotretinoin

- Finasteride

Question 11

Drugs - 14 days (3)

Answer 11

• Clopidogrel
• Ticlopidine
• Vorapaxar

Question 12

Drugs - 7 days (5)

Answer 12

• Prasugrel
• Ticagrelor
• Warfarin
• Heparin
• Fondaparinux

Question 13

Drugs - 3 days (1)

Answer 13

• Piroxicam

Question 14

Drugs - 2 days (5)

Answer 14

• Deltaparin
• Enoxaparin
• Clabigatran
• Apixaban
• Endoxaban

Question 15

HTLV-1 infection

Answer 15

Indefinite

Question 16

Receiving money or drugs for sex

Answer 16

Indefinite

Question 17

Paying for sex.

Answer 17

12 months

Question 18

Hx of syphilis, gonorrhea

Answer 18

12 months

Question 19

Incarceration >72 hours

Answer 19

12 months

Question 20

Travel to malaria endemic area

Answer 20

12 months

Question 21

Non-sterile needles (tatoo)

Answer 21

12 months

Question 22

Lived for >5 years in malaria endemic areas (regardless of prophylaxis)

Answer 22

3 years

Question 23

Minimum Hb/Hct

Answer 23

12.5/38%

Question 24

Autologous donor: minimum Hb/Hct

Answer 24

11/33%

Question 25

Plasmaphoresis: minimum weight

Answer 25

50 kg (110 lbs)

Question 26

Plasmaphoresis: "frequent" donor program

Answer 26

2 donations/wk; at least 2 days apart Others: 4 weeks apart

Question 27

Plateletphersis interval

Answer 27

2/week; at least 2 days apart <25 in 1 year

Question 28

Deferral period following single unit of RBCs with platelets and or plasma

Answer 28

8 weeks

Question 29

Deferral period following double RBC donation by apheresis

Answer 29

16 weeks

Question 30

Donor Adverse Reactions - Vasovagal Reaction: - S/S - Treatment

Answer 30

Donor Adverse Reactions - Vasovagal Reaction: - Bradycardia, Hypotension, Dizzy, Syncope, Sweating, N/V - Elevate feet, cold compress to head/neck

Question 31

Donor Adverse Reactions - Hypovolemia: - S/S - Treatment

Answer 31

Donor Adverse Reactions - Hypovolemia: - Tachycardia w/ Hypotension - Fluids by mouth or IV

Question 32

Donor Adverse Reactions - Hyperventilation: - S/S - Treatment

Answer 32

Donor Adverse Reactions - Hyperventilation: - Rapid/Shallow breathing - Hypocapnia (+/- twitching/seizure) - Breath in paper bag

Question 33

Donor Adverse Reactions - Citrate effect: - Only seen in what donors - MOA - S/S - Treatment (mild/severe)

Answer 33

Apheresis donors only - Hypocalcemia - Perioral tingling, N/V, arrhythmias, seizures - Mild - slow infusion - Severe - Calcium Carbonate (oral)

Question 34

ABO grouping: | -Forward typing

Answer 34

Donor RBCs w/ anti-A and anti-B reagents

Question 35

ABO grouping: | -Reverse typing

Answer 35

Donor serum w/ A1 and B reagent RBCs

Question 36

Rh Type testing is determined by using what?

Answer 36

Anti-D reagent

Question 37

If anti-D test is negative what is the next step? | -How is this peformed

Answer 37

Test for weak D | -Addition of antihuman globulin (AHG) and extended incubation

Question 38

The antibody screen is required for what donors? (2)

Answer 38

- History of transfusion | - History Pregnancy

Question 39

``` What is the blood type: Forward Grouping -Anti-A - 0 -Anti-B - 0 Reverse Grouping -A cells - 4+ -B cells - 4+ ```

Answer 39

Group O

Question 40

``` What is the blood type: Forward Grouping -Anti-A - 4+ -Anti-B - 4+ Reverse Grouping -A cells - 0 -B cells - 0 ```

Answer 40

Group AB

Question 41

``` What is the blood type: Forward Grouping -Anti-A - 4+ -Anti-B - 0 Reverse Grouping -A cells - 0 -B cells - 4+ ```

Answer 41

Group A

Question 42

``` What is the blood type: Forward Grouping -Anti-A - 0 -Anti-B - 4+ Reverse Grouping -A cells - 4+ -B cells - 0 ```

Answer 42

Group B

Question 43

What are the required Infectious Diseases tests on donor blood? (8)

Answer 43

- HBsAg - Anti-HBc - Anti-HCV - HCV RNA - Anti-HIV1/2 - HIV1 RNA - Anti-HTLV-I/II - RPR (serologic test for syphilis)