Blood flow (exam 3) Flashcards

(41 cards)

1
Q

BP should linearly inc. with inc. work loads, but if it’s not behaving correctly, when do u stop exercise?

A

if systolic decreases by 20 mmHG

or if diastolic inc. by 10 mmHG

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2
Q

formula for BP/ MAP

A

BP= Q (SVxHR) x TPR

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3
Q

does Max BP change with training?

A

no, ur max is ur max

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4
Q

Nervous control of BP: long term solution

A

kidneys and fluid balance (through blood volume)

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5
Q

Nervous control of BP: short term

A

CV system (HR slows or speeds up to control BP)

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6
Q

what role do the atria play in controling BP?

A

stretch receptors in the atria (barroreceptors-mechanical stretch), detect stretch in atria walls due to inc. blood volume and they signal the brain, whoa hello too much volume/pressure here, so the brain triggers vasodilation in the vv of the legs to decrease the amount coming back to the heart to fast while simultaneously inc. ADH release to make sure it doesn’t decrease too much all at once.

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7
Q

what does the vasomotor center of the medulla do?

A

uses a pressor and depressor to regulate BP

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8
Q

where does the vasomotor sensor receive stim. from?

A

input from sensors all over the body (chemoreceptors, baroreceptors, mm afferent receptors) and from cortex and hypothalamus

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9
Q

what does stim of the pressors/ depressors do?

A

pressor- inc. HR and force of contraction, constricts vascular smooth mm in arterioles and what little their is in vv
depressor= exact opp. of all that- dec. HR, dec. force of contraction, vasodilates, etc.

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10
Q

what happens to end diastolic filling with age?

A

it decreases

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11
Q

define velocity

A

rate, speed at which blood is traveling

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12
Q

define flow

A

volume, amount of blood/time

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13
Q

types of flow

A

laminar- linear, smooth

turbulent- bubbly, going all diff. directions (happens at divergences,tears/flaps in vessel walls, plaques)

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14
Q

Darcy’s law

A

Q (flow this time)= [(P1-P2)/R]

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15
Q

what vessels have the lowest velocity of flow in order to allow for blood product exchange between them and their target tissues?

A

capillaries

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16
Q

in what vessels is vascular resistance highest?

A

arterioles (tiny holes, makes cells get down to one lane, and they have mm walls- think traffic going from three lane highway to one lane walled off bc of construction)

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17
Q

what is defined as the total vascular resistance from the aorta to the R atrium

18
Q

what vessels have lowest vascular resistance to flow?

19
Q

velocity of flow is _______ proportional to the cross sectional area of the vessel

A

inversely (think, big pipe= flows slower, tiny pipe= must flow faster)

20
Q

if length of tube doubles, what happens to flow?

A

decreases by 50% (duh, can now only move halfway thru in the same amount of time)

21
Q

if tube radius doubles, what happens to flow?

A

increases 16 fold! (pouring a gallon of milk through a PVC pipe or through a drinking straw)

22
Q

if viscosity of the liquid doubles, what happens to flow?

A

it decreases by half (think pouring water through a funnel or pouring honey through the same funnel)

23
Q

where is blood flow the fastest? when does this principal become a problem?

A

fastest in center of vessel bc encounters no resistance there, around the sides of the vessel it has friction from the vessel walls. this becomes problematic if vessels aren’t elastic enough (due to connective tissue disorders like marfan’s syndrome, or due to plaque buildup) to vasodilate when pressure is too great and they tear or break

24
Q

what does the shearing forces of the blood friction on the vessel walls trigger to be releases?

A

nitric oxide–>tells brain to vasodilate

25
these types of vessels have inc. motor tone compared to these vessels which always need to stay open?
heart, mm, skin= inc. tone | cerebral and renal= dec. tone bc they always need to be open!
26
what does bradykinin do
vasodilates
27
what does norepinephrine do?
vasoconstriction
28
what does angiotensin II do?
vasoconstriction
29
what does vasopressin (ADH) do?
vasoconstriction
30
what does the symp. NS do?
inc. vasomotor tone
31
what does the parasymp. NS do?
dec. vasomotor tone
32
what is a potent vasodilator and is released with inc. metabolic activity or when ATP levels are low... ?
adenosine!
33
what does K+ do and how does it do it?
vasodilation of blood vessels, hyperkalemia= decreases Ca which is what goes to the vascular smooth mm cells to make them contract, less Ca= less contracting=relaxation and dilation ;)
34
what do arachidonic acid and histamine do to tone?
can inc. or dec. tone
35
what does myogenic mechanisms in vasc. smooth mm cells do?
inc. tone
36
what do endothelial factors such as nitric oxide and endothelin do?
inc. or dec. tone
37
what is reactive hyperemia?
momentary inc. of blood flow after brief period of total ischemia, like after getting ur BP taken, or having a turnicate on. RELEASE the flood gates!
38
active hyperemia
actively increasing blood flow, like by running
39
loss of what cells will keep vessels from being able to dilate or constrict?
endothelial cells
40
what happens to vessels that aren't used as much, say from injury or say in a SCI when a person doesn't use their leg mm so their vessels don't pump to the mm near as much anymore?
the vessels constrict, but blood flow and diameter will increase with training or e-stim, etc. things that get those mm working again.
41
will the affected limb ever match the nonaffected limb again?
no, it will improve, but not match it, as far as blood flow goes.