BLOOD FLUKES Flashcards

1
Q

where do blood fluke species inhabit?

A

portal bloodstream of vertebrates

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2
Q

oriental blood fluke

A

s. japonicum

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3
Q

visceral blood fluke

A

s. haematobium

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4
Q

manson’s blood fluke

A

s. mansoni

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5
Q

s. japonicum & s. mansoni adult worms migrate to

A

mesenteric venules of bowel/rectum

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6
Q

s. hametobium adult worms migrate to

A

venous plexus of bladder

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7
Q

organ of maturation of schistosomes in humans

A

liver

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8
Q

freq. found on superior mesenteric veins

A

s. japonicum

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9
Q

occurs often in the inferior mesenteric veins

A

s. mansoni

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10
Q

schostosomes: drains small intestine

A

s. japonicum

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11
Q

s. haematobium most often inhabits in the ?

A

vesicular and pelvic venous plexus of the bladder

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12
Q

found in rectal venules

A

s. haematobium

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13
Q

only schistosoma in small intestine

A

schistosoma japonicum

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14
Q

it is what s. japonicum males forms wherein females will go inside for copulation; where female worm resides

A

gynecophoral canal

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15
Q

describe s. japonicum ova shape and spine

A

shape: ovoidal, rounded or pearshaped
spine: CURVED hook/spine or LATERAL KNOB

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16
Q

most commonly presented and most important characteristic of s. japonicum

A

lateral KNOB

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17
Q

miracidium hatches from the egg in what kind of water environment & temperature

A

slightly alkaline clean water; 25C to 31C

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18
Q

miracidium stimulus

A

light (phototactic)

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19
Q

infective stage of snail

A

miracidia

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20
Q

emerges from daughter sporocysts

A

cercariae

21
Q

infective stage to humans

A

cercaria

22
Q

mode of transmission

A

skin penetration

23
Q

adapted to survive in SERUM or physiologic SALINE at 37C

A

schistosomulae

24
Q

develops from cercariae after skin penetration

A

schistosomulae

25
Q

what is found at the exterior portion of the male s. mansoni

A

tuberculate exterior

26
Q

describe the ova shape and spine of the s. mansoni

A

shape: elongated oblong
ova spine: LATERAL SPINE

27
Q

describe the ova shape and spine of the s. haematobium

A

shape: elongated oblong
ova spine: TERMINAL spine

28
Q

s. japonicum intermediate host

A

oncomelania hupensis quadrasi

29
Q

s. mansoni intermediate host

A

biomphalaria
australorbis

30
Q

s. haematobium intermediate host

A

bulinus

31
Q

local cutaneous hypersensitivity; pruritic papular rash that develops 24 hrs after exposure

A

cercarial dermatitis/swimmer’s itch

32
Q

systemic hypersensitivity; may have lymphadenopathy, hepatic, and splenic enlargement due to the migration of worms through the circulation

A

katayama fever

33
Q

gastrointestinal involvement = enlargement of liver, spleen, anemia, ascites, has CNS involvement

A

chronic stage

34
Q

sensitive for MODERATE and HEAVY infections; not adequate for light infections (<10 g stool)

A

Merthiolate-Iodine Formalin Concentration Technique

35
Q

for ENUMERATION OF EGGS; used for evaluating epidemiology, effect of control measures, drug trials

A

kato katz technique

36
Q

indirect hemagglutination using adult worm and egg antigens

A

Cercarian Hullen Reaction (CHR)

37
Q

Cercarian Hullen Reaction (CHR) positive reaction is indicated by

A

formation of PRECERCARIAL SHEATH around cercariae

38
Q

CHR positive in CSF =

A

wrinkled surface

39
Q

CHR positive in serum =

A

bubbles

40
Q

based on patient serum precipitation with lyophilized eggs or purified live eggs identifed under microscope

A

Circumoval Precipitin Test (CPT)

41
Q

Circumoval Precipitin Test (CPT) is useful for the diagnosis of ?

A

s. mansoni
s. japonicum

42
Q

blood flukes treatment

A

praziquantel

43
Q

found in Africa and pockets of the Middle East

A

s. haematobium

44
Q

found in China, Philippines, Sulawesi

A

s. japonicum

45
Q

found across sub-Saharan Africa, Brazil, Venezuela, Suriname (South America), Carribean, Arabian Peninsula (sporadic)

A

s. mansoni

46
Q

3 less common human-infecing schistosomes

A

s. mekongi
s. intercalatum
s. guineensis

47
Q

blood flukes epidemiology in the Philippines

A

Sorsogon
Oriental Mindoro
Samar
Leyte
Bohol
Mindanao (except: Misamis Oriental)

48
Q

blood flukes: prevention

A

avoid s