Blood, Hemostasis, and Blood Groups Flashcards

1
Q

What type of tissue is blood considered?

A

Connective. because of extracellular matrix surrounded.
Only fluid tissue of the body

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2
Q

What percent of our body weight is blood?

A

8%. 5-6 in men/ 4-5 in women

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3
Q

What should the pH be between?

A

7.35 and 7.45

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4
Q

Why would the color of the blood be dark?

A

Deoxygenation- when O2 is unloaded
Low O2

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5
Q

Why would the color of the blood be dark?

A

Low O2

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6
Q

What is hemocrit and the normal value between?

A

percentage of blood volume that consists of erythrocytes. Normal value 45(+/-5%)

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7
Q

Blood functions?

A

Distribution of respiratory gases, nutrients and metabolic waste products
Hormone transport
Regulates body temp, body pH and total blood volume
Protection against infections

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8
Q

Plasma?

A

Liquid part of blood
55% of blood volume

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9
Q

Formed Elements?

A

RBC
WBC
Platelets

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10
Q

Blood Plasma?

A

Consists of 90% water acting as a solvent for other substances
Proteins being the majority of “other substances”
-produced by the liver

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11
Q

What 3 groups are blood plasma divided into?

A

Albumins
Globulins
Other solutes- nutrients, electrolytes, gases, hormones, and metabolic wastes

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12
Q

Erythrocytes?

A

transport if oxygen from the lungs to the tissue
depending on hemoglobin
No nucleus or mitochondria. Cannot use the oxygen to generate ATP
Life span of 100-120 days

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13
Q

Hemocytoblast?

A

blood cell formation

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14
Q

Hemopoiesis/ Hematopoiesis

A

production of all formed elements occurring in red bone marrow
driven by influence of hormones and growth factors depending on the needs of the body

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15
Q

Type O

A

neither A nor B antigens, naturally makes antibodies against both therefore cannot receive from anyone other than O
-universal donor

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16
Q

AB Blood

A

-both A and B antigens, making no antibodies or it would attack itself
-Universal recipient

17
Q

Type A

A

A antigens and naturally makes antibodies against B antigen

18
Q

Type B

A

B antigens and naturally makes antibodies against A antigen

19
Q

Rh antigen

A

Considered +, if not then you are -
-Antibodies are only formed after exposure (during birth or via transfusin)

20
Q

Hemoglobin

A

4 chains; 2 alpha and 2 beta
carrying 4 O2 molecules
can bind to other gases
bind with CO2 to form carbaminohemoglobin

20
Q

Hemoglobin

A

4 chains; 2 alpha and 2 beta
carrying 4 O2 molecules
can bind to other gases
bind with CO2 to form carbaminohemoglobin

21
Q

Hypoxia and its normal values

A

Lack of RBC leading to oxygen deficiency in tissues
-Men 16 (+/-2)
-Women 14 (+/-2)

22
Q

Anemia

A

abnormal low hemoglobin
fatigue, paleness, shortness of breath, chills

23
Q

Aplastic Anemia

A

low # of RBC
caused by destruction or inhibition of red bone marrow

24
Q

Hemolytic Anemia

A

RBC’s are destroyed faster than produced

25
Q

Hemorrhagic Anemia

A

acute or chronic blood loss

26
Q

Iron- deficiency anemia

A

lack of iron
increased loss due to chronic blood loss
impaired iron absorption

27
Q

Pernicious Anemia

A

deficiency in B12
lack of intrinsic factor
nutritional deficiency
effecting the nervous system and other systems

28
Q

Sickle Cell Anemia

A

recessive disorder-abnormal genetic code for hemoglobin
hemoglobin s
-long chains in low oxygen situations
-changing the shape of RBC to sickle-shaped
-block small vessels and lead to a lack of oxygen in tissues

29
Q

Thalassemia

A

Absent or faulty globin chain
common in people with Mediterranean heritage
lead to erythrocyte being thin, delicate and deficient in hemoglobin

30
Q

Leukocytes WBC’s

A

less than 1% of total blood volume
moves through tissue spaces by positive chemotaxis

31
Q

Leukopoiesis

A

WBC formation

32
Q

Granulocytes

A

Larger and shorter lived than RBC’s
phagocytic (A type of immune cell that can surround and kill microorganisms, ingest foreign material, and remove dead cells)

33
Q

Neutrophils

A

Most numerous WBC’s