Blood Investigations Flashcards
(24 cards)
What are the main investigations for Haematological disease
Blood film
Blood count
Clotting screen
How can Anaemia be screened
RBC
-Hb and MCV
What type of infection is common with Neutrophilia
Bacterial infection
Neutropenia indicates what types of disease
Myeloma
Lymphoma
Lymphocytosis indicates what type of infection
Chronic
What constituents can bloods be screened for
RBC Neutrophils Lymphocytes Platelets Eosinophils Monocytes
What cells are raised in parasitic infection
Eosinophils
What can increased monocytes suggest
Myelodysplastic Syndrome
What is Myelodysplastic syndrome
A rare blood cancer w/ Increased monocytes
What does the clotting screen look at
Prothrombin time INR APTT Bleeding time Clotting time
What clotting pathway does PT and INR share
Extrinsic
What does prothrombin time indicate
Extrinsic coagulation speed
10-13.5s
What is a normal INR value
0.8 - 1.2
What is the INR value if a patient is on Warfarin
2-3
When can INR be seen as raised
Warfarin use / Low Vit K
Anticoagulant use
Liver disease
DIC
How is INR measured
Patient INR/ Normal INR
What clotting pathway is APTT a part of
Intrinsic
What does APTT measure
Intrinsic coagulation speed
35-45s
When is APTT raised (But PT normal)
Heparin use
Haemophillia
VWF disease
The time taken to convert fibrinogen to fibrin is known as what
Clotting time
What does Bleeding time assess
The function of platelets
What factors are involved in the extrinsic Coag. Cascade
12, 11, 9, 8
What factors are involed in the Intrinsic Coag. Cascade
3 to 7
What factors are involved in the common pathway of coagulation cascade
10 and 2
10 to 2 by factor 5
