blood physiology- lab 1 hematology Flashcards

(39 cards)

1
Q

Transport functions of blood

A

deliver O2 and nutrients such as glucose and amino acids to body tissue cells, disposes of waste products such as CO2 and Nitrogenous waste, and transporting hormones to various parts of the body to regulate an organ function

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2
Q

other blood functions

A

regulate internal body temperature, body defense to prevent infection, acid/base balance, blood clotting to prevent blood loss after a blood vessel wall is torn

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3
Q

erythrocytes

A

red blood cells, responsible for transport of O2 to body tissue cells and removal of CO2 waste from interstitial fluid that surrounds body cells

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4
Q

leukocytes

A

white blood cells, defend body from viruses, bacteria, and other pathogens and microorganisms that can cause infection

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5
Q

thrombocytes

A

platelets, help prevent blood loss by forming collections of cells at the site of damage called clots when blood vessel walls are torn

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6
Q

of the 3 cell type, which is considered a true cell

A

leukocytes. erythrocytes and thrombocytes are not true because they can’t mitotically divide (no nucleus)

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7
Q

hemtopoieses

A

blood cell production

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8
Q

normal blood cell values

A

erythrocytes
males- 5.4 plus minus .8 mm cubed
females 4.8 plus. minus .6 mm cubed

leukpcytes
males 7-9000 per mm cubed
females 5-7000 per mm cubed

thrombocytes
150k to 400k per mm cubed, average 300k per mm cubed

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9
Q

hemoglobin

A

a molecule responsible for binding and carrying O2, to body tissue cells to help remove CO2 from body tissue.

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10
Q

if each gram of hemoglobin in the erythrocyte is completely O2 saturated, erythrocyte carries how much O2

A

1.34 ml O2. if there is 15 g Hb per 100 mL blood, 20 mL O2 carried in 100 mL blood

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11
Q

polycythemia

A

abnormally high number of RBC

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12
Q

anemia

A

occurs when there is an abnormal decrease in RBC number

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13
Q

anemic hypoxia

A

shortage in O2 delivery to body tissue cells

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14
Q

hematocrit

A

percent volume of blood that is made up of only erythrocytes

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15
Q

heparin

A

chemical that prevents formation of clots that would make blood drawing difficult

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16
Q

erythropoietin

A

erythrocyte strict regulation via this Horm one in the kidneys

17
Q

normal values of hematocrit

A

male
46% (43-49%)
female
41% (36-45%)

18
Q

which gender has a higher percentage of hematocrit

19
Q

why do males have a higher hematocrit percentage usually

A

testosterone influences erythropoietin

20
Q

how to calculate hematocrit

A

RBC height (mm) / heigh of red cells and plasma (mm) x 100

21
Q

normal hemoglobin values

A

male 15.4 Hb/100mL (between 13.6-17.2)
female 13.3 Hb/100mL
(between 11.5-15.0)

22
Q

what level is considered anemic for blood hemoglobin / when do we see major anemia issues

A

10 g Hb per 100 mL
we see issues at 7.5 g Hb per 100 mL

23
Q

how can measuring blood hemoglobin levels be accomplished

A

potassium cyanide (KCN)

24
Q

what colored compound is produced when hemoglobin is exposed to KCN (potassium cyanide)

A

cyanmethemoglobin

25
how to measure total blood Hb
total blood Hb (g) = blood volume (mL blood) x hemoglobin concentration (g Hb/mL blood)
26
total O2 carrying capacity
= total g Hb x 1.34 mL O2/g Hb
27
normal blood volume for humans
males- 79 mL per kg body weight plus minus 10% females- 65 mL blood per kg body weight plus minus 10 1kg is 2.2 pounds
28
two leukocytes classes
granulocytes (neutrophils, eosinophils, basophils) and agranulocytes (small/large lymphocytes and monocytes)
29
neutrophils, eosinophils, and basophil percents
n- 65% with multilobed nucleus e- 2-4% bilobed nucelus b- .5% bilobed nucelus
30
small lymphocytes, large lymphocytes, and monocytes %
smal- 20-25% large nucelus large- 3% large oval nucelus monocytes- 3-7% large, deep indented nucleus
31
never let monkeys eat bananas
order from large to small for neutrophils, lymphocytes, monocytes, eosinophils, basophils
32
penia/cytosis means what
less/more
33
neutropenia
abnormally low number of neutrophils
34
neutrophilic leukocytosis
abnormally high number of neutrophils
35
lymphocytosis
abnormally high number of lymphocytes
36
lymphocytopenia
abnormally low number of lymphocytes in blood
37
eosinophilia
abnormally high number of eosinophils
38
monocytosis
abnormally high number of monocytes
39
normal leukocyte count
4500-11000 WBCs per microliter of blood