blood products

Question 1

List 4 reasons that a blood transfusion might be given

Answer 1

Restore O2 carrying capacity
Restore blood volume
Provide blood components
Treat sepsis

Question 2

Blood products

Whole blood

Answer 2

Fresh whole blood

Stored whole blood

Question 3

Plasma

Answer 3

Fresh plasma

Frozen plasma

Question 4

Platelet concentrate

Answer 4

not available in UK

Question 5

Packed red blood cells - action

Answer 5

restore oxygen carrying capacity

Question 6

Non-Labile clotting factors

Answer 6

(non fragile)

Question 7

Non-Labile clotting factors

Answer 7

(non fragile)

Question 8

Fresh whole blood - function

Answer 8

++ restores oxygen carrying capacity and blood volume ++

Question 9

Fresh whole blood - constituents

Answer 9

RBCs, WBCs, platelets, plasma proteins, Calcium, fibrogen

Question 10

Fresh whole blood -indications for use

Answer 10

haemorrhage, haemolysis, aplastic anaemia, thrombocytopaenia, coagulation disease, DIC. hypovolaemia

Question 11

Fresh whole blood - shelf life

Answer 11

4 - 8 hours

Question 12

Fresh whole blood - constituents

Answer 12

RBCs, WBCs, platelets, plasma proteins, Calcium, fibrogen

Question 13

Fresh whole blood -indications for use

Answer 13

haemorrhage, haemolysis, aplastic anaemia, thrombocytopaenia, coagulation disease, DIC. hypovolaemia

Question 14

Fresh whole blood - shelf life

Answer 14

4 - 8 hours

Question 15

Fresh whole blood - storage

Answer 15

FRESH WHOLE BLOOD SHOULD NOT BE REFRIGERATED

Question 16

Stored whole blood - function

Answer 16

restores oxygen carrying capacity and blood volume

Question 17

stored whole blood - constituents

Answer 17

RBCs, WBCs, plasma proteins,

Question 18

stored whole blood - indications for use

Answer 18

plasma replacement, haemolysis, anaemia, hypovolaemia, coagulopathy, DIC, bone marrow disease

Question 19

stored whole blood - shelf life

Answer 19

coagulant - citrate phosphate dextorse - 21 days

coagulant - citrate phosphate dextrose adenine - 35 days

Question 20

Stored whole blood - storage

Answer 20

1 - 6 C for 8 hours.
store upright
bags should be gently mixed by inversion several times a week

Question 21

Packed red blood cells - constituents

Answer 21

PRBCs suspended in small volume of plasma and 100ml SAG-M

Question 22

Packed red blood cells - indications for use

Answer 22

Regenerative anaemia, non-regenerative anaemia, Acute blood loss, IMHA, Chronic blood loss- parasitism, bone marrow disorders

Question 23

Packed red blood cells - Shelf life

Answer 23

PRBC’s stored in SAG-M have a shelf life of 42 days

Question 24

Packed red blood cells - storage

Answer 24

1-6C

Store upright
space for air to circulate
bags mixed gently

Question 25

Fresh frozen Plasma (FFP) - product

Answer 25

plasma that has been seperated within 8 hours of collection

Question 26

Fresh frozen Plasma (FFP) - action

Answer 26

volume expansion, replace plasma factors, replace liable clotting factors

Question 27

Fresh frozen Plasma (FFP) - constituents

Answer 27

all plasma proteins (including labile CF)

Question 28

Fresh frozen Plasma (FFP) - indications for use

Answer 28

Coagulopathies, von Willebrands, loss of protiens, burns, GIT disorders, haemophillia A. DIC, pancreatitis, hypovolaemia.

Question 29

Fresh frozen Plasma (FFP) - shelf life

Answer 29

12 months

Question 30

Fresh frozen Plasma (FFP) - storage

Answer 30

-18C

Question 31

Frozen Plasma (FP) - product

Answer 31

plasma that has been separated from whole blood, >12 hours after collection but within the expiry date of the whole blood.

Question 32

Frozen Plasma (FP) - action

Answer 32

provides plasma factors and non liable clotting factors. Volume expansion

Question 33

Frozen Plasma (FP) - constituents

Answer 33

albuminm - non liable clotting factors

Question 34

Frozen Plasma (FP) - indications for use

Answer 34

deficiencies of non liable clotting factors.

Question 35

Frozen Plasma (FP) - shelf life

Answer 35

FP in CPD has a shelf life of 5 years

Question 36

Frozen Plasma (FP) - storage

Answer 36

-18C

Question 37

Platelet concentrate - Product

Answer 37

concentration of platelets

Question 38

Platelet concentrate - action

Answer 38

provides platelets

Question 39

Platelet concentrate - indications for use

Answer 39

thrombocytopaenia

Question 40

Platelet concentrate - shelf life

Answer 40

5 days

Question 41

Platelet concentrate - storage

Answer 41

22C

Question 42

Cryo - supernatant - constituents

Answer 42

non labile clotting factorsd, albumin and other plasma proteins

Question 43

Cryo - supernatant - indications of use

Answer 43

plasma protein deficients, hypovolaemia, coagulopathies

Question 44

Cryo - supernatant - shelf life

Answer 44

12 months

Question 45

Cryo - supernatant - storage

Answer 45

-18C

Question 46

Cryo - supernatant - storage

Answer 46

-18C

Question 47

Cryo - precipitate - action

Answer 47

restores labile clotting factors and plasma proteins

Question 48

Cryo - precipitate - constituents

Answer 48

20% fibrogren , 50% clotting factor VII | 30% comprised of clotting factors

Question 49

Cryo - precipitate - indications for use

Answer 49

Inherited clotting factor deficiencies such as haemophillia A and VWD. Topical haemostatic in surgery.

Question 50

Cryo - precipitate - shelf life

Answer 50

12 months

Question 51

Cryo - precipitate - storage

Answer 51

-18C