Blood Study Guide Flashcards

1
Q

What are the 3 major plasma proteins?

A

Albumin,
Fibrinogen,
Globulins

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2
Q

What is hemopoiesis?

A

The productions of blood

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3
Q

What properties of blood contribute to its viscosity?

A

Erythrocyte count,
Amount of plasma,
Hemoglobin concentration

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4
Q

Why would a female have hematocrit values lower than a male?

A

Men produce androgens which increases RBC production

Hematocrit is inversely proportional to body fat.

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5
Q

What is anemia?

A

Low RBC’s

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6
Q

What is Sickle Cell Disease?

A

hereditary hemoglobin defects

-caused by recessive allele

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7
Q

What are the nutritional needs for erythropoiesis?

A

Iron
Copper
Folic Acid
Vit. B12 and C

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8
Q

What is Leukemia?

A

Elevated white blood cells

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9
Q

What organelles are lacking in erythrocytes?

A

Mitochondria

Nucleus

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10
Q

Where are RBC’s broken down?

A

Spleen then liver breaks down hemoglobin

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11
Q

Where is the hemoglobin broken down?

A

liver

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12
Q

What would increase erythropoiesis?

A

Erythropoietin

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13
Q

What is erythropoietin and where is it produced?

A

stimulates bone marrow to increase RBC’s

Erythropoietin is produced in kidneys

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14
Q

What is hemostasis?

A

cessation of bleeding

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15
Q

What mechanisms are involved in hemostasis (stopping the bleeding)?

A
  1. vascular spasm

2. platelet plug 3. Blood coagulation

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16
Q

How does your body prevent inappropriate clotting?

A

platelet repulsion&Thrombin Repulsion&Natural Anticoagulants

17
Q

What is heparin?

A

an anti-coagulant

18
Q

What is hemophilia?

A

deficiency of clotting factors

19
Q

What are the clotting disorders?

A

Hemophilia,Hematomas,Thrombosis,Embolus,Infarction

20
Q

How do we clinically prevent clots?

A

Vit K antagonist (coumerin)

21
Q

How do we clinically dissolve clots?

A

streptokinase
TPA
hementin

22
Q

How are blood clots dissolved?

A

Fibrinolysis

23
Q

What is included in a Complete CBC?

A
  1. Hematocrit
  2. Hemoglobin concentration
  3. Total count for RBC’s, reticulocytes, WBC’s & platlets
  4. Differential WBC count
  5. RBC size and hemoglobin concentration per RBC
24
Q

What are the 5 leukocytes?

A
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
25
Q

What are Neutrophils function?

A

bacterial infections 3-5 lobed nucleus

26
Q

What are Lymphocytes function?

A

antibodies
antigen presenting cells
immune cells/memory (T&B cells)

27
Q

Monocytes function?

A

Antigen presenting cells
Becomes tissue macrophages
horseshoe shape

28
Q

Eosinophils function?

A

Parasitic infections and allergies

2 lobes

29
Q

Basophil functions?

A

secrete histamine and heparin

30
Q

What is the most abundant Leukocyte?

A

Neutrophils

31
Q

What is the most universal blood donor?

A

Type O

32
Q

Universal recipient of blood?

A

Type AB

33
Q

What are the nonprotein components of blood?

A

hormones, glucose, waste, gases

34
Q

What are the steps to Erythropoiesis?

A

low oxygen sensed by kidneys that secrete erythropoietin which goes to the red bone marrow to make more RBC