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Y3 Haematology > Blood Transfusions > Flashcards

Blood Transfusions Flashcards

1
Q

what are the minimum criteria that need to be met to give blood?

A

Hb >135 in men and >125 in women

weight >50kg

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2
Q

how are red cells stored?

A

4C

up to 35 days

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3
Q

how is FFP stored?

A

at -30C

for up to 3 years

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4
Q

how are platelets stored?

A

at 22C

for 7 days

with agitation

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5
Q

what does FFP stand for?

A

fresh frozen plasma

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6
Q

what is FFP a source of?

A

clotting factors

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7
Q

what is cryoprecipitate and what does it contain?

A

further procesed FFP

a source of fibrinogen

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8
Q

what determines a person’s blood group?

A

their red cell antigens

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9
Q

what codes for a persons ABO group?

A

the ABO gene on chromosome 9

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10
Q

which gene is dominant in the ABO system?

A

A and B co-dominant over O

there is no O antigen, a patient just lacks the A/B gene

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11
Q

what is the most common ABO group?

A

O

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12
Q

what are the possible genotypes in people with blood group O?

A

OO

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13
Q

what are the possible genotypes in people with blood group A?

A

AA or AO

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14
Q

what are the possible genotypes in people with blood group B?

A

BB or BO

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15
Q

what are the possible genotypes in people with blood group AB?

A

AB

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16
Q

how is the ABO group inherited?

A

one ABO gene from each parent

17
Q

what ABO types of blood can be given to people with blood group O?

A

O

18
Q

what ABO types of blood can be given to people with blood group A?

A

O

A

19
Q

what ABO types of blood can be given to people with blood group B?

A

O
B

20
Q

what ABO types of blood can be given to people with blood group AB?

A

O
A
B
AB

21
Q

what does landsteiner’s law state?

A

when an individual lacks the A or B antigen, the corresponding antibody is produced in their plasma

i.e. group A = antibodies for B

22
Q

what antibodies are present in patients with blood group A?

A

anti B

23
Q

what antibodies are present in patients with blood group B?

A

anti A

24
Q

what antibodies are present in patients with blood group AB?

A

none

25
Q

what antibodies are present in patients with blood group O?

A

anti A

anti B

26
Q

is it more common to be rhesus positive or negative?

A

positive

85% of the population are RhD positive

27
Q

what are the possible genotypes in an RhD+ patient?

A

DD or Dd

28
Q

what are the possible genotypes in an RhD- patient?

A

dd

Y3 Haematology (23 decks)

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